- ￥8000 - 10800
- DIMA BIOTECH/缔码生物
- 武汉
- FLP100038
- 2026年04月07日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 保质期：
12个月
- 英文名：
Human CLDN6 full length protein-VLP
- 库存：
In Stock
- 供应商：
缔码生物（武汉）科技有限公司
- 规格：
50μg/100μg
| 规格： | 50μg | 产品价格： | ￥8000.0 |
|---|---|---|---|
| 规格： | 100μg | 产品价格： | ￥10800.0 |
| 产品类型 | Full Length Transmembrane Proteins |
|---|---|
| 靶点 | CLDN6 |
| Uniprot ID | P56747 |
| 别名 | Claudin 6; Claudin-6; Skullin;Claudin6 |
| 背景 | Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This gene encodes a component of tight junction strands, which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. The gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member CLDN9 on chromosome 16. |
| 蛋白家族 | Transmembrane |
| 信号通路 | Cell adhesion molecules (CAMs), Leukocyte transendothelial migration, Tight junction |
| 产品英文名称 | Human CLDN6 full length protein-VLP |
| 分子量 | The human full length CLDN6 Protein has a MW of 23 kDa |
| 标签 | C-Flag Tag |
| 有无偶联 | Unconjugated |
| 表达宿主 | HEK293 |
| 组分 | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| 货期 | In Stock |
| 储存与运输 | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| 应用范围 | Research use only |
Figure1. Elisa plates were pre-coated with 0.5μg/per well purified human CLDN6 full length VLP. Serial diluted anti-CLDN6 monoclonal antibody (BME100082) solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-CLDN6 monoclonal antibody binding with CLDN6 full length VLP is 5.616ng/ml.风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
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结构 研究表明 LRRK2 蛋白酶突变是导致帕金森病的关键原因之一。 2021 年 6 月 8 日，圣裘德儿童研究医院孙吉教授团队在 Cell 上发表研究论文 Structural analysis of the full-length human LRRK2，该研究首次解析了人类 LRRK2 全长蛋白的高分辨率结构，为人类战胜帕金森病提供了理论参考。图 6：来源 Cell 7. Lacent: 父母学历越高，所生小孩死亡率越低 2021 年 6 月 10 日，挪威科技大学 Terje
receptor8. Mouse apoB is a large protein of 4,515 amino acids and is expressed predominantly in liver and jejunum. apoB mRNA is subject to post-transcriptional editing, and the unedited and edited transcripts encode the full-length protein apoB-100
位点，RNA聚合酶在此和DNA结合，并由此开始转录过程。 蛋白质（Protein）：一种由一条或者多条肽链构成的大分子。每条肽链上核苷酸的顺序是由基因外显子部分的碱基序列决定的。蛋白质是细胞、组织和器官的重要组成部分，每种蛋白质都具有特定的功能。酶、抗体和激素等都是蛋白质。 嘌呤（Purine）：一种含氮的单环结构物。是核苷酸的重要组成部分，有腺嘌呤A和鸟嘌呤G两种。 嘧啶（Pyrimidine）：一种含氮的双环结构，是核苷酸的重要组成部分。分为胞嘧啶C，胸腺嘧啶T和尿嘧啶U三种
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