Anti-Denosumab Polyclonal Anti

宿主	Rabbit
特异性	The product is specific for Denosumab. This antibody serves as an excellent positive control for Denosumab immunogenicity (ADA) assays.
经测试应用	ELISA: 1:4000-1:8000
免疫原	Denosumab
状态	Liquid
保存溶液	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
浓度	0.6 mg/ml
克隆类型	Polyclonal
同种型	IgG
应用	ELISA
靶标	Rabbit polyclonal to Prolia.
纯化方式	Purified by antigen affinity column.
Accession号	CAS: 615258-40-7
稳定性和存储	The product can be stored for 2 - 3 weeks at 2 to 8°C or for up to 12 months at -20°C. Avoid repeated freezing and thawing cycles.
背景	Denosumab with trade name Prolia, is an FDA-approved drug for the treatment of patients with osteoporosis, treatment-induced bone loss, metastases to bone, and giant cell tumor of bone. Denosumab is a fully human monoclonal antibody that works as a RANK ligand (RANKL) inhibitor. Denosumab can bind RANKL, preventing RANKL from activating RANK, its receptor on the osteoclast surface.
备注	Antibodysystem can customize this product per customer's request including product size, buffer components, etc. For research use only.

AntibodySystem Laboratories SAS was established in 2019 in France as an independent brand entity focused on the research, development, and production of protein and antibody reagents in the life sciences field. Our mission is to provide high-quality protein and antibody products to life science researchers worldwide. AntibodySystem's extensive product range includes traditional polyclonal antibodies, classic housekeeping antibodies, tag antibodies, high-activity proteins, in vivo functional antibodies, low-background flow cytometry antibodies, high-specificity nanobodies, specialized small molecule antibodies, premium phospho-specific antibodies, DNA/RNA antibodies, PEG antibodies, and more—spanning over ten product series.
Currently, AntibodySystem's product lines cover multiple research areas, including 48 types of viruses and superbugs, parasites, tumors, Alzheimer's disease, Parkinson's disease, hypersensitivity and allergic reactions, immune suppression, and immune activation.