- ￥6768
- AntibodySystem
- 234.4 ng/mL - 15,000 ng/mL
- KDD12603
- France
- 2025年07月14日
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- 详细信息
- 技术资料
- 库存：
999
- 供应商：
AntibodySystem
- 检测范围：
234.4 ng/mL - 15,000 ng/mL
- 检测方法：
Colorimetric
- 应用：
Used for the quantitative determination of Ranibizumab concentration in serum and plasma.
- 标记物：
HRP
- 样本：
Plasma, Serum
- 规格：
96T
| 描述 | PRINCIPLE OF THE ASSAY This assay employs the quantitative competitive enzyme immunoassay technique. Recombinant human VEGFA antigen has been pre-coated onto a microplate. Standards or samples are premixed with biotin-labeled antibody and then pipetted into the wells. Ranibizumab in the sample competitively binds to the pre-coated protein with biotin-labeled Ranibizumab. After washing away any unbound substances, Streptavidin-HRP is added to the wells. Following a wash to remove any unbound enzyme reagent, a substrate solution is added to the wells and color develops in inversely proportion to the amount of Ranibizumab bound in the initial step. The color development is stopped and the intensity of the color is measured. | ||||||||||||||||||||||||||||||||||||||||||
| 应用 | Used for the quantitative determination of Ranibizumab concentration in serum and plasma. | ||||||||||||||||||||||||||||||||||||||||||
| 稳定性和存储 | When the kit was stored at the recommended temperature for 6 months, the signal intensity decreased by less than 20%. For unopened kits, if you want to prolong the storage time, please store the Standard, Detection A, Detection B and Microplate at - 20℃, the rest reagents should be store at 4℃. | ||||||||||||||||||||||||||||||||||||||||||
| 检测方法 | Colorimetric | ||||||||||||||||||||||||||||||||||||||||||
| 精准度 |
Intra-Assay Precision (Precision within an assay): <20% Three samples of known concentration were tested sixteen times on one plate to assess intra-assay precision. Inter-Assay Precision (Precision between assays): <20% Three samples of known concentration were tested in twenty four separate assays to assess inter-assay precision.
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| 样本类型 | Plasma, Serum | ||||||||||||||||||||||||||||||||||||||||||
| 实验类型 | Quantitative | ||||||||||||||||||||||||||||||||||||||||||
| 检测范围 | 234.4 ng/mL - 15,000 ng/mL | ||||||||||||||||||||||||||||||||||||||||||
| 回收率 | 80-120% | ||||||||||||||||||||||||||||||||||||||||||
| 背景 | Ranibizumab is a monoclonal antibody fragment (Fab) created from the same parent mouse antibody as bevacizumab. Ranibizumab was developed by Genentech and is marketed in the United States by Genentech and elsewhere by Novartis, under the brand name Lucentis. Ranibizumab is used to treat wet age-related macular degeneration (AMD; an ongoing disease of the eye that causes loss of the ability to see straight ahead and may make it more difficult to read, drive, or perform other daily activities). It is also used to treat macular edema after retinal vein occlusion (an eye disease caused by blockage of blood flow from the eye that leads to blurry vision and vision loss), diabetic macular edema (an eye disease caused by diabetes that can lead to vision loss), and diabetic retinopathy (damage to the eyes caused by diabetes). It inhibits angiogenesis by inhibiting Vascular endothelial growth factor A (VEGF-A), and its effectiveness is similar to that of bevacizumab. Its rates of side effects also appear similar. However, ranibizumab typically costs $2,000 a dose, while the equivalent dose of bevacizumab typically costs $50. | ||||||||||||||||||||||||||||||||||||||||||
| 别名 | Fab-12 variant Y0317, RhuFab, CAS: 347396-82-1 | ||||||||||||||||||||||||||||||||||||||||||
| 运输 | 2-8 ℃ | ||||||||||||||||||||||||||||||||||||||||||
| 备注 | For Research Use Only. | ||||||||||||||||||||||||||||||||||||||||||
Founded in 2019 in France, AntibodySystem Laboratories SAS is a dedicated, independent brand focused on producing high-quality protein and antibody reagents for life science research. We aim to equip researchers worldwide with reliable products for foundational studies in life sciences. AntibodySystem's comprehensive product lineup includes traditional polyclonal antibodies, housekeeping antibodies, tag antibodies, high-performance proteins, in vivo functional antibodies, low-background antibodies for flow cytometry, nanobodies with high specificity, specialized small molecule antibodies, premium phospho-specific antibodies, DNA/RNA antibodies, PEG antibodies, and more.
Our products are designed for various research areas, supporting studies on 48 types of viruses, superbugs, parasites, cancer, Alzheimer's disease, Parkinson's disease, allergic responses, immune suppression, and immune activation.
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