Emibetuzumab ELISA Kit ELISA试剂盒

Emibetuzumab ELISA Kit ELISA试剂

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  • ¥6768
  • AntibodySystem已认证
  • 0.31-5 μg/mL
  • 0.156 μg/ml
  • KDC34201
  • France
  • 2025年07月14日
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    代理商
    2钻石会员
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    • 详细信息
    • 技术资料
    • 库存

      999

    • 供应商

      AntibodySystem

    • 检测范围

      0.31-5 μg/mL

    • 检测方法

      Colorimetric

    • 应用

      ELISA

    • 标记物

      HRP

    • 样本

      Plasma, Serum

    • 灵敏度

      0.156 μg/ml

    • 规格

      96T

    Emibetuzumab ELISA Kit ELISA试剂

    稳定性和存储The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 10% prior to the expiration date under appropriate storage condition.
    检测方法Colorimetric
    精准度

    CV<20%

    样本类型Plasma, Serum
    实验类型Quantitative
    灵敏度0.156 μg/ml
    检测范围0.31-5 μg/mL
    回收率80-120%
    背景Emibetuzumab (as known as LY2875358) is a humanized immunoglobulin G4 monoclonal bivalent anti-MET antibody that blocks MET signaling. This drug was developed by Eli Lilly & Company and has been used in trials studying the treatment of Advanced Cancer, Renal Cell Carcinoma, Hepatocellular Cancer, Gastric Adenocarcinoma, and Non-Small Cell Lung Cancer, among others. In preclinical models, emibetuzumab inhibited growth of tumors that are dependent on MET, including tumors that exhibit HGF-dependent and HGF-independent biology. Administration of a single dose of emibetuzumab resulted in continuous reduction of MET protein expression for 14 days in mouse xenografts. Emibetuzumab demonstrated dose-dependent, single-agent activity in various MET-expressing tumor models, and additive effects were observed in combination with erlotinib for reducing tumor volume in lung cancer mouse xenograft models. In Phase 1 dose escalation studies, emibetuzumab monotherapy was well tolerated in patients with advanced solid tumors, including gastric cancer, with no dose-limiting toxicities.
    别名LA480, LY-2875358, CAS: 1365287-97-3
    运输2-8 ℃
    备注For Research Use Only.

    Founded in 2019 in France, AntibodySystem Laboratories SAS is a dedicated, independent brand focused on producing high-quality protein and antibody reagents for life science research. We aim to equip researchers worldwide with reliable products for foundational studies in life sciences. AntibodySystem's comprehensive product lineup includes traditional polyclonal antibodies, housekeeping antibodies, tag antibodies, high-performance proteins, in vivo functional antibodies, low-background antibodies for flow cytometry, nanobodies with high specificity, specialized small molecule antibodies, premium phospho-specific antibodies, DNA/RNA antibodies, PEG antibodies, and more.
    Our products are designed for various research areas, supporting studies on 48 types of viruses, superbugs, parasites, cancer, Alzheimer's disease, Parkinson's disease, allergic responses, immune suppression, and immune activation.

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