L-茶氨酸 *Sigma货号：SMB00395-500MG/

一般描述

L-茶氨酸是谷氨酰胺的类似物，也是绿茶的成分之一
应用
Safety and Efficacy of AlphaWave L-Theanine Supplementation for 28 Days in Healthy Adults with Moderate Stress: A Randomized, Double-Blind, Placebo-Controlled Trial.: This clinical trial demonstrates that L-theanine supplementation effectively reduces stress and improves cognitive function without adverse effects (Moulin et al., 2024). (Moulin et al., 2024).
Inhibitory Role of L-theanine, a Structural Analogue of Glutamate, Against GluR5 Kainate Receptor and its Prospective Utility Against Excitotoxicity.: The study examines L-theanine′s potential in protecting against neurotoxicity by inhibiting specific glutamate receptors (Deb and Borah, 2024). (Deb and Borah, 2024).
L-theanine abates oxidative stress and mitochondrial dysfunction in myocardial ischemia-reperfusion injury by positively regulating the antioxidant response.: This research demonstrates the cardioprotective effects of L-theanine, highlighting its role in reducing oxidative stress and improving mitochondrial function during heart injuries (García-Niño et al., 2024). (García-Niño et al., 2024).

生化/生理作用

L-茶氨酸可调节几种抗肿瘤药物的活性，据报道，它可刺激人类胚胎干细胞的自我更新
L-茶氨酸与 AMPA、红藻氨酸、NMDA 和 I 型 mGlu 受体结合
茶氨酸能够与大鼠皮层神经元的 AMPA、钾盐镁矾和 NMDA 甘氨酸受体结合但亲和力低于谷氨酸
已对其作为谷氨酸盐转运抑制剂进行了研究，防止荷 M5076 卵巢肉瘤小鼠细胞摄取谷氨酸盐，并增加多柔比星对 M5076 小鼠肿瘤生长的影响
其他说明 茶氨酸是一种谷氨酰胺的氨基酸类似物，存在于绿茶中