NALM6细胞

NALM-6 /NALM-6 细胞系/NALM-6 细胞株/NALM-6 人B淋巴白血病细胞

Cell line name NALM-6

Synonyms Nalm-6; NALM 6; Nalm 6; NALM6; Nalm6; NALM-6-M1

Accession CVCL_0092

Resource Identification Initiative To cite this cell line use: NALM-6 (RRID:CVCL_0092)

Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).

Part of: COSMIC cell lines project.

Part of: LL-100 blood cancer cell line panel.

Part of: MD Anderson Cell Lines Project.

Part of: NCI Pediatric Preclinical Testing Program (PPTP) cell line panel.

Population: Caucasian.

Doubling time: 25 hours (PubMed=25984343); 19 hours (PubMed=20922763); 40.2 hours (PubMed=8847894); ~36 hours (DSMZ=ACC-128).

Microsatellite instability: Instable (MSI-high) (PubMed=10739008; PubMed=11226526; PubMed=31068700; Sanger).

Omics: Deep exome analysis.

Omics: DNA methylation analysis.

Omics: Deep quantitative proteome analysis.

Omics: Protein expression by reverse-phase protein arrays.

Omics: shRNA library screening.

Omics: SNP array analysis.

Omics: Transcriptome analysis by microarray.

Omics: Transcriptome analysis by RNAseq.

Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.

PubMed=9067587; DOI=10.1038/sj.leu.2400571

Uphoff C.C., MacLeod R.A.F., Denkmann S.A., Golub T.R., Borkhardt A., Janssen J.W.G., Drexler H.G.

Occurrence of TEL-AML1 fusion resulting from (12;21) translocation in human early B-lineage leukemia cell lines.

Leukemia 11:441-447(1997)

 

PubMed=9510473; DOI=10.1111/j.1349-7006.1998.tb00476.x; PMCID=PMC5921588

Hosoya N., Hangaishi A., Ogawa S., Miyagawa K., Mitani K., Yazaki Y., Hirai H.

Frameshift mutations of the hMSH6 gene in human leukemia cell lines.

Jpn. J. Cancer Res. 89:33-39(1998)

 

PubMed=9680106; DOI=10.1016/S0145-2126(98)00050-2

Matsuo Y., Drexler H.G.

Establishment and characterization of human B cell precursor-leukemia cell lines.

Leuk. Res. 22:567-579(1998)

 

PubMed=9738977; DOI=10.1111/j.1349-7006.1998.tb03275.x; PMCID=PMC5921886

Takizawa J., Suzuki R., Kuroda H., Utsunomiya A., Kagami Y., Joh T., Aizawa Y., Ueda R., Seto M.

Expression of the TCL1 gene at 14q32 in B-cell malignancies but not in adult T-cell leukemia.

Jpn. J. Cancer Res. 89:712-718(1998)

 

PubMed=10490826; DOI=10.1038/sj.onc.1202874

Fu X.-Y., McGrath S., Pasillas M., Nakazawa S., Kamps M.P.

EB-1, a tyrosine kinase signal transduction gene, is transcriptionally activated in the t(1;19) subset of pre-B ALL, which express oncoprotein E2a-Pbx1.

Oncogene 18:4920-4929(1999)

 

PubMed=10695022

Matsuo Y., Nishizaki C., Drexler H.G.

Efficient DNA fingerprinting method for the identification of cross-culture contamination of cell lines.

Hum. Cell 12:149-154(1999)

 

PubMed=10739008; DOI=10.1016/S0145-2126(99)00182-4

Inoue K., Kohno T., Takakura S., Hayashi Y., Mizoguchi H., Yokota J.

Frequent microsatellite instability and BAX mutations in T cell acute lymphoblastic leukemia cell lines.

Leuk. Res. 24:255-262(2000)

 

PubMed=11021758; DOI=10.1038/sj.leu.2401891

Majka M., Rozmyslowicz T., Honczarenko M.J., Ratajczak J., Wasik M.A., Gaulton G.N., Ratajczak M.Z.

Biological significance of the expression of HIV-related chemokine coreceptors (CCR5 and CXCR4) and their ligands by human hematopoietic cell lines.

Leukemia 14:1821-1832(2000)

 

DOI=10.1016/B978-0-12-221970-2.50457-5

Drexler H.G.

The leukemia-lymphoma cell line factsbook.

(In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001)

 

PubMed=11226526; DOI=10.1016/S0145-2126(00)00121-1

Inoue K., Kohno T., Takakura S., Hayashi Y., Mizoguchi H., Yokota J.

Corrigendum to: Frequent microsatellite instability and BAX mutations in T cell acute lymphoblastic leukemia cell lines Leukemia Research 24 (2000), 255-262.

Leuk. Res. 25:275-278(2001)