AtT20细胞

AtT-20/AtT-20细胞系/AtT-20细胞株/AtT-20小鼠垂体瘤细胞

Cell line name AtT-20

Synonyms AtT 20; ATT-20; AtT20

Accession CVCL_2300

Resource Identification Initiative To cite this cell line use: AtT-20 (RRID:CVCL_2300)

Comments Doubling time: ~3 days (Note=Lot 11152004) (JCRB=JCRB9098).

Omics: SNP array analysis.

Omics: Transcriptome analysis by microarray.

Derived from site: In situ; Pituitary gland; UBERON=UBERON_0000007.

Disease Mouse pituitary gland neoplasms (NCIt: C24037)

Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)

Breed/subspecies: LAF1.

Hierarchy Children:

CVCL_XA98 (AtT-20-FlpIn) CVCL_4W08 (AtT-20/D16v) CVCL_C6XD (AtT-20/HNP)

CVCL_1G40 (AtT-20ins) CVCL_1G39 (AtT-20ins4b/1)

Category Cancer cell line

STR profile Source(s): Procell

 

Markers:

Mouse STR 1-1 11,15

Mouse STR 1-2 13,17

Mouse STR 2-1 15,16

Mouse STR 3-2 10,14

Mouse STR 4-2 18.3

Mouse STR 5-5 16,18

Mouse STR 6-4 18

Mouse STR 6-7 13,15

Mouse STR 7-1 25.2

Mouse STR 8-1 15

Mouse STR 11-2 15,16

Mouse STR 12-1 16,17

Mouse STR 13-1 17.2,18.2

Mouse STR 15-3 17,22.3

Mouse STR 17-2 14

Mouse STR 18-3 17,18

Mouse STR 19-2 11,12

Mouse STR X-1 25

 

Run an STR similarity search on this cell line

Publications

PubMed=13874682; DOI=10.1073/pnas.48.7.1184; PMCID=PMC220930

Buonassisi V., Sato G.H., Cohen A.I.

Hormone-producing cultures of adrenal and pituitary tumor origin.

Proc. Natl. Acad. Sci. U.S.A. 48:1184-1190(1962)

 

DOI=10.1007/BF02618370

Stulberg C.S., Coriell L.L., Kniazeff A.J., Shannon J.E.

The animal cell culture collection.

In Vitro 5:1-16(1970)

 

PubMed=6317196; DOI=10.1016/0092-8674(83)90187-3

Moore H.-P.H., Walker M.D., Lee F., Kelly R.B.

Expressing a human proinsulin cDNA in a mouse ACTH-secreting cell Intracellular storage, proteolytic processing, and secretion on stimulation.

Cell 35:531-538(1983)

 

PubMed=2177466; DOI=10.1007/BF02624442

Vedder H.

Serum-free culture of AtT 20 pituitary cells: a system for neuroendocrine studies under defined conditions.

In Vitro Cell. Dev. Biol. 26:1068-1072(1990)

 

PubMed=8383976; DOI=10.1677/jme.0.0100025

Farrell W.E., Stewart M.F., Clark A.J.L., Crosby S.R., Davis J.R.E., White A.

Glucocorticoid inhibition of ACTH peptides: small cell lung cancer cell lines are more resistant than pituitary corticotroph adenoma cells.

J. Mol. Endocrinol. 10:25-32(1993)

 

PubMed=15541569; DOI=10.1016/j.mce.2004.07.018

Ooi G.T., Tawadros N., Escalona R.M.

Pituitary cell lines and their endocrine applications.

Mol. Cell. Endocrinol. 228:1-21(2004)

 

PubMed=21214938; DOI=10.1186/1471-2164-12-14; PMCID=PMC3024950

Atwood B.K., Lopez J., Wager-Miller J., Mackie K., Straiker A.

Expression of G protein-coupled receptors and related proteins in HEK293, AtT20, BV2, and N18 cell lines as revealed by microarray analysis.

BMC Genomics 12:14.1-14.14(2011)

 

PubMed=25277546; DOI=10.1186/1471-2164-15-847; PMCID=PMC4198738

Didion J.P., Buus R.J., Naghashfar Z., Threadgill D.W., Morse H.C. 3rd, Pardo-Manuel de Villena F.

SNP array profiling of mouse cell lines identifies their strains of origin and reveals cross-contamination and widespread aneuploidy.

BMC Genomics 15:847.1-847.11(2014)