AML12细胞

AML-12 AML12/AML-12 AML12细胞系/AML-12 AML12细胞株/AML-12 AML12小鼠正常肝细胞

Cell line name    AML12
Synonyms    AML-12; AML 12; Alpha Mouse Liver 12
Accession    CVCL_0140
Resource Identification Initiative    To cite this cell line use: AML12 (RRID:CVCL_0140)
Comments    Doubling time: 37 hours (PubMed=7904757).
Genetic integration: Method=Transgenic mouse; Gene=HGNC; 11765; TGFA.
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Cell type: Hepatocyte; CL=CL_0000182.
Species of origin    Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: CD-1 MT42 transgenic.
Hierarchy    Children:
CVCL_D6AU (HyCyte AML12 KO-mIgf2)    CVCL_E1J5 (HyCyte AML12 KO-mNsun6)    CVCL_D8DT (Ubigene AML12 Atp7b KO)
CVCL_D8DU (Ubigene AML12 Cs KO)    CVCL_D8DV (Ubigene AML12 Faah KO)    CVCL_D8DW (Ubigene AML12 Fasn KO)
CVCL_D8DX (Ubigene AML12 Ldlr KO)
Sex of cell    Male
Age at sampling    5M
Category    Spontaneously immortalized cell line
STR profile    Source(s): Ubigene=YC-D022

Markers:
Mouse STR 4-2    20.3
Mouse STR 5-5    14,15
Mouse STR 6-4    16
Mouse STR 6-7    12
Mouse STR 12-1    19
Mouse STR 15-3    21.3
Mouse STR 18-3    21
Mouse STR X-1    26

Run an STR similarity search on this cell line
Publications    
PubMed=7904757; DOI=10.1073/pnas.91.2.674; PMCID=PMC43011
Wu J.C., Merlino G.T., Fausto N.
Establishment and characterization of differentiated, nontransformed hepatocyte cell lines derived from mice transgenic for transforming growth factor alpha.
Proc. Natl. Acad. Sci. U.S.A. 91:674-678(1994)