HMY1细胞

HMY-1细胞HMY-1细胞HMY-1;人黑色素瘤细胞Cell line name HMY-1

Synonyms HMY1

Accession CVCL_2950

Resource Identification Initiative To cite this cell line use: HMY-1 (RRID:CVCL_2950)

Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).

Population: Japanese.

Doubling time: 37 hours (PubMed=6239887).

Omics: Deep exome analysis.

Omics: SNP array analysis.

Omics: Transcriptome analysis by RNAseq.

Derived from site: Metastatic; Left inguinal lymph node; UBERON=UBERON_0001542.

Sequence variations

Mutation; HGNC; 1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (DepMap=ACH-001522).

HLA typing Source: PubMed=26589293

Class I

HLA-A A*02:06,24:02

HLA-B B*39:01,52:01

HLA-C C*07:02,12:02

Disease Melanoma (NCIt: C3224)

Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell Male

Age at sampling 62Y

Category Cancer cell line

STR profile Source(s): DepMap=ACH-001522; JCRB=JCRB1018; PubMed=25877200

 

Markers:

Amelogenin X,Y

CSF1PO 12

D3S1358 15

D5S818 12

D7S820 11,14

D8S1179 14

D13S317 11,13

D16S539 10

D18S51 14,17

D21S11 30,32.2

FGA 22

Penta D 14

Penta E 17,20

TH01 6

TPOX 11

vWA 17,19

 

Run an STR similarity search on this cell line

Publications

PubMed=6239887; DOI=10.1111/j.1346-8138.1984.tb01486.x

Kondo S., Sato N., Sato K., Hozumi Y., Aso K.

Establishment of cell lines from human malignant melanomas and their application to the assessment of natural killer-like cytotoxicity.

J. Dermatol. 11:328-334(1984)

 

PubMed=25485619; DOI=10.1038/nbt.3080

Klijn C., Durinck S., Stawiski E.W., Haverty P.M., Jiang Z.-S., Liu H.-B., Degenhardt J., Mayba O., Gnad F., Liu J.-F., Pau G., Reeder J., Cao Y., Mukhyala K., Selvaraj S.K., Yu M.-M., Zynda G.J., Brauer M.J., Wu T.D., Gentleman R.C., Manning G., Yauch R.L., Bourgon R., Stokoe D., Modrusan Z., Neve R.M., de Sauvage F.J., Settleman J., Seshagiri S., Zhang Z.-M.

A comprehensive transcriptional portrait of human cancer cell lines.

Nat. Biotechnol. 33:306-312(2015)

 

PubMed=25877200; DOI=10.1038/nature14397

Yu M., Selvaraj S.K., Liang-Chu M.M.Y., Aghajani S., Busse M., Yuan J., Lee G., Peale F.V., Klijn C., Bourgon R., Kaminker J.S., Neve R.M.

A resource for cell line authentication, annotation and quality control.

Nature 520:307-311(2015)

 

PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878

Scholtalbers J., Boegel S., Bukur T., Byl M., Goerges S., Sorn P., Loewer M., Sahin U., Castle J.C.

TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.

Genome Med. 7:118.1-118.7(2015)