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T25
【c666-1】c666-1细胞/c666-1细胞/c666-1人鼻咽癌细胞Cell line name C666-1
Synonyms c666-1; C6661
Accession CVCL_7949
Resource Identification Initiative To cite this cell line use: C666-1 (RRID:CVCL_7949)
Comments Population: Chinese.
Virology: Contains a complete EBV genome (strain C666-1) which has been sequenced (PubMed=23915735; PubMed=25787276).
Doubling time: 3.5 days (PubMed=10449618).
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Omics: Transcriptome analysis by RNAseq.
Disease Nasopharyngeal carcinoma (NCIt: C3871)
Nasopharyngeal carcinoma (ORDO: Orphanet_150)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
PubMed=10449618; DOI=10.1002/(SICI)1097-0215(19990924)83:1<121::AID-IJC21>3.0.CO;2-F
Cheung S.-T., Huang D.P., Hui A.B.-Y., Lo K.-W., Ko C., Tsang Y.S., Wong N., Whitney B.M., Lee J.C.-K.
Nasopharyngeal carcinoma cell line (C666-1) consistently harbouring Epstein-Barr virus.
Int. J. Cancer 83:121-126(1999)
PubMed=12645650; DOI=10.1016/S0165-4608(02)00657-X
Wong N., Hui A.B.-Y., Fan B.-L., Lo K.-W., Pang E., Leung S.-F., Huang D.P., Johnson P.J.
Molecular cytogenetic characterization of nasopharyngeal carcinoma cell lines and xenografts by comparative genomic hybridization and spectral karyotyping.
Cancer Genet. Cytogenet. 140:124-132(2003)
PubMed=18196576; DOI=10.1002/ijc.23374
Chan S.Y.-Y., Choy K.-W., Tsao S.-W., Tao Q., Tang T., Chung G.T.-Y., Lo K.-W.
Authentication of nasopharyngeal carcinoma tumor lines.
Int. J. Cancer 122:2169-2171(2008)
PubMed=23915735; DOI=10.1186/1750-9378-8-29; PMCID=PMC3734220
Tso K.K.-Y., Yip K.Y.-L., Mak C.K.-Y., Chung G.T.-Y., Lee S.-D., Cheung S.-T., To K.-F., Lo K.-W.
Complete genomic sequence of Epstein-Barr virus in nasopharyngeal carcinoma cell line C666-1.
Infect. Agents Cancer 8:29.1-29.4(2013)
PubMed=24991015; DOI=10.1128/JVI.01457-14; PMCID=PMC4178894
Strong M.J., Baddoo M., Nanbo A., Xu M., Puetter A., Lin Z.
Comprehensive high-throughput RNA sequencing analysis reveals contamination of multiple nasopharyngeal carcinoma cell lines with HeLa cell genomes.
J. Virol. 88:10696-10704(2014)
PubMed=25787276; DOI=10.1128/JVI.03614-14; PMCID=PMC4442510
Palser A.L., Grayson N.E., White R.E., Corton C., Correia S., Ba Abdullah M.M., Watson S.J., Cotten M., Arrand J.R., Murray P.G., Allday M.J., Rickinson A.B., Young L.S., Farrell P.J., Kellam P.
Genome diversity of Epstein-Barr virus from multiple tumor types and normal infection.
J. Virol. 89:5222-5237(2015)
PubMed=26116706; DOI=10.1096/fj.14-266718
Ye F., Chen C.-G., Qin J., Liu J., Zheng C.-Y.
Genetic profiling reveals an alarming rate of cross-contamination among human cell lines used in China.
FASEB J. 29:4268-4272(2015)
PubMed=30405107; DOI=10.1038/s41467-018-06889-5; PMCID=PMC6220246
Lin W.-T., Yip Y.-L., Jia L., Deng W., Zheng H., Dai W., Ko J.M.-Y., Lo K.-W., Chung G.T.-Y., Yip K.Y.-L., Lee S.-D., Kwan J.S.-H., Zhang J., Liu T.-F., Chan J.Y.-W., Kwong D.L.-W., Lee V.H.-F., Nicholls J.M., Busson P., Liu X.-F., Chiang A.K.-S., Hui K.-F., Kwok H., Cheung S.-T., Cheung Y.-C., Chan C.-K., Li B., Cheung A.L.-M., Hau P.-M., Zhou Y., Tsang C.-M., Middeldorp J.M., Chen H.-L., Lung M.L., Tsao S.-W.
Establishment and characterization of new tumor xenografts and cancer cell lines from EBV-positive nasopharyngeal carcinoma.
Nat. Commun. 9:4663.1-4663.17(2018)
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文献和实验*发表【中文论文】请标注:由上海酶研生物科技有限公司提供;
*发表【英文论文】请标注:From Shanghai EK-Bioscience Biotechnology Co., Ltd.
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