ARPE19细胞

ARPE-19/ARPE-19细胞系/ARPE-19细胞株/ARPE-19人永生化视网膜色素上皮细胞Cell line name ARPE-19

Synonyms ARPE19; Adult Retinal Pigment Epithelial cell line-19; NTC-200; NTC200

Accession CVCL_0145

Resource Identification Initiative To cite this cell line use: ARPE-19 (RRID:CVCL_0145)

Comments Doubling time: 55 hours (Note=From cell counting), 65 hours (Note=From absorbance) (DOI=10.5897/IJBMBR2013.0154).

Omics: Deep proteome analysis.

Omics: Deep quantitative phosphoproteome analysis.

Omics: Metabolome analysis.

Omics: Transcriptome analysis by microarray.

Anecdotal: The number 19 in the cell line name is due to the fact that this cell line was established from a 19-year-old male who died from head trauma in a motor vehicle accident.

Misspelling: APRE-19; Note=Occasionally.

Derived from site: In situ; Eye, retina, retinal pigment epithelium; UBERON=UBERON_0001782.

Cell type: Retinal pigment epithelial cell; CL=CL_0002586.

PubMed=8698076; DOI=10.1006/exer.1996.0020

Dunn K.C., Aotaki-Keen A.E., Putkey F.R., Hjelmeland L.M.

ARPE-19, a human retinal pigment epithelial cell line with differentiated properties.

Exp. Eye Res. 62:155-169(1996)

 

PubMed=11504951; DOI=10.1073/pnas.171266298; PMCID=PMC55557

Lund R.D., Adamson P., Sauve Y., Keegan D.J., Girman S.V., Wang S.-M., Winton H.L., Kanuga N., Kwan A.S.L., Beauchene L., Zerbib A., Hetherington L., Couraud P.-O., Coffey P., Greenwood J.

Subretinal transplantation of genetically modified human cell lines attenuates loss of visual function in dystrophic rats.

Proc. Natl. Acad. Sci. U.S.A. 98:9942-9947(2001)

 

PubMed=14551534; PMCID=PMC2819117

Rogojina A.T., Orr W.E., Song B.K., Geisert E.E. Jr.

Comparing the use of Affymetrix to spotted oligonucleotide microarrays using two retinal pigment epithelium cell lines.

Mol. Vis. 9:482-496(2003)

 

PubMed=16262907; DOI=10.1186/1471-2415-5-25; PMCID=PMC1291373

Sharma R.K., Orr W.E., Schmitt A.D., Johnson D.A.

A functional profile of gene expression in ARPE-19 cells.

BMC Ophthalmol. 5:25.1-25.10(2005)

 

PubMed=21697133; DOI=10.1167/iovs.11-7479

Oshikawa M., Tsutsui C., Ikegami T., Fuchida Y., Matsubara M., Toyama S., Usami R., Ohtoko K., Kato S.

Full-length transcriptome analysis of human retina-derived cell lines ARPE-19 and Y79 using the vector-capping method.

Invest. Ophthalmol. Vis. Sci. 52:6662-6670(2011)

 

DOI=10.5897/IJBMBR2013.0154

Iloki Assanga S.B., Gil-Salido A.A., Lewis Lujan L.M., de Jesus Rosas-Durazo A., Acosta-Silva A.L., Rivera-Castaneda E.G., Rubio-Pino J.L.

Cell growth curves for different cell lines and their relationship with biological activities.

Int. J. Biotechnol. Mol. Biol. Res. 4:60-70(2013)

 

PubMed=24251032; DOI=10.1155/2013/216359; PMCID=PMC3819763

Pasovic L., Utheim T.P., Maria R., Lyberg T., Messelt E.B., Aabel P., Chen D.-F., Chen X.-J., Eidet J.R.

Optimization of storage temperature for cultured ARPE-19 cells.

J. Ophthalmol. 2013:216359.1-216359.11(2013)

 

PubMed=25177495; DOI=10.1155/2014/801787; PMCID=PMC4142280

Kuznetsova A.V., Kurinov A.M., Aleksandrova M.A.

Cell models to study regulation of cell transformation in pathologies of retinal pigment epithelium.

J. Ophthalmol. 2014:801787.1-801787.18(2014)

 

PubMed=27499609; PMCID=PMC4961466

Wang Y., Sang A.-M., Zhu M.-H., Zhang G.-W., Guan H.-J., Ji M., Chen H.

Tissue factor induces VEGF expression via activation of the Wnt/beta-catenin signaling pathway in ARPE-19 cells.

Mol. Vis. 22:886-897(2016)

 

PubMed=28978645; DOI=10.1074/jbc.M117.812677; PMCID=PMC5712622

Chiang C.-K., Tworak A., Kevany B.M., Xu B., Mayne J., Ning Z.-B., Figeys D., Palczewski K.

Quantitative phosphoproteomics reveals involvement of multiple signaling pathways in early phagocytosis by the retinal pigmented epithelium.

J. Biol. Chem. 292:19826-19839(2017)

 

PubMed=29476476; DOI=10.1007/978-1-4939-7680-5_17

Fasler-Kan E., Aliu N., Wunderlich K., Ketterer S., Ruggiero S., Berger S., Meyer P.

The retinal pigment epithelial cell line (ARPE-19) displays mosaic structural chromosomal aberrations.

Methods Mol. Biol. 1745:305-314(2018)

 

PubMed=30167441; DOI=10.1016/j.dib.2018.06.103; PMCID=PMC6111057

Koirala D., Beranova-Giorgianni S., Giorgianni F.

Data-independent proteome analysis of ARPE-19 cells.

Data Brief 20:333-336(2018)

 

PubMed=31254428; DOI=10.1111/ceo.13578

Churm R., Dunseath G.J., Prior S.L., Thomas R.L., Banerjee S., Owens D.R.

Development and characterization of an in vitro system of the human retina using cultured cell lines.

Clin. Exp. Ophthalmol. 47:1055-1062(2019)