HS-5人骨髓基质细胞

HS-5/HS-5细胞系/HS-5细胞株/HS-5人骨髓基质细胞

Cell line name HS-5

Synonyms HS5

Accession CVCL_3720

Resource Identification Initiative To cite this cell line use: HS-5 (RRID:CVCL_3720)

Comments Group: Patented cell line.

Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-11882.

Population: Caucasian.

Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6.

Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7.

Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.

Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).

Omics: Deep quantitative proteome analysis.

Derived from site: In situ; Bone marrow, stroma; UBERON=UBERON_0007195.

Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)

Originate from same individual CVCL_0E35 ! HS-23

CVCL_0E34 ! HS-27

Sex of cell Male

Age at sampling 30Y

Category Transformed cell line

STR profile Source(s): ATCC=CRL-3611; Technion Genomics Center

 

Markers:

Amelogenin X,Y

CSF1PO 10,11

D1S1656 15,17.3

D2S441 11

D2S1338 22,26

D3S1358 14,17

D5S818 12

D7S820 12

D8S1179 13,16

D10S1248 13,15

D12S391 19,21

D13S317 11

D16S539 11

D18S51 12,15

D19S433 15

D21S11 29,30

D22S1045 15,16

FGA 21,24

Penta D 10,13

Penta E 5,6

TH01 7,9

TPOX 8

vWA 18,19

PubMed=7849321; DOI=10.1182/blood.V85.4.997.bloodjournal854997

Roecklein B.A., Torok-Storb B.

Functionally distinct human marrow stromal cell lines immortalized by transduction with the human papilloma virus E6/E7 genes.

Blood 85:997-1005(1995)

 

Patent=US7129086

Torok-Storb B., Roecklein B.A., Johnson G.

Human marrow stromal cell lines which sustain hematopoiesis.

Patent number US7129086, 31-Oct-2006