EL4小鼠淋巴瘤细胞

EL4/EL4细胞系/EL4细胞株/EL4小鼠淋巴瘤细胞

Cell line name EL4

Synonyms EL-4; EL 4; E.L.4

Accession CVCL_0255

Resource Identification Initiative To cite this cell line use: EL4 (RRID:CVCL_0255)

Comments Part of: Tumor Immunology Bank (TIB) collection from Salk (transferred to ATCC in 1981).

Doubling time: ~15-20 hours (DSMZ=ACC-831); ~14 hours (Note=Lot 10262015), ~12 hours (Note=Lot 02052018) (JCRB=JCRB1350).

Transformant: ChEBI; CHEBI:254496; 7,12-dimethyltetraphene (DMBA; dimethylbenzanthracene).

Omics: HLA class I peptidome analysis by proteomics.

Derived from site: In situ; Ascites; UBERON=UBERON_0007795.

Cell type: T-cell; CL=CL_0000084.

Disease Mouse precursor T cell lymphoblastic lymphoma/leukemia (NCIt: C21925)

Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)

Breed/subspecies: C57BL/6N.

Hierarchy Children:

CVCL_3505 (E.G7-OVA) CVCL_A0DM (EL-4 6.1) CVCL_E3E7 (EL-4/cCD20)

CVCL_8603 (EL-4ad) CVCL_B6PH (EL4-B7-2) CVCL_A4BN (EL4-Luc2 [ATCC])

CVCL_5J22 (EL4-luc2 [Caliper]) CVCL_F943 (EL4-TK) CVCL_A0PX (EL4-Zbtb1 KO)

CVCL_B6PK (EL4/E2) CVCL_3818 (EL4.BU) CVCL_5680 (EL4.BU.1.OUAr.1.1)

CVCL_0256 (EL4.E1) CVCL_5681 (EL4.IL-2) CVCL_B6PG (EL4B7-1)

CVCL_B6PL (EL4B7-2) CVCL_E1JT (HyCyte EL4 KO-mErlin1) CVCL_E1JU (HyCyte EL4 KO-mTmem176b)

Sex of cell Sex unspecified

Age at sampling Age unspecified

Category Cancer cell line

Publications

PubMed=14801344; DOI=10.1038/bjc.1950.36; PMCID=PMC2007731

Gorer P.A.

Studies in antibody response of mice to tumour inoculation.

Br. J. Cancer 4:372-379(1950)

 

PubMed=4867923

Glynn J.P., McCoy J.L., Fefer A.

Cross-resistance to the transplantation of syngeneic Friend, Moloney, and Rauscher virus-induced tumors.

Cancer Res. 28:434-439(1968)

 

PubMed=4099030; DOI=10.1126/science.171.3966.75

Mohit B., Fan K.

Hybrid cell line from a cloned immunoglobulin-producing mouse myeloma and a nonproducing mouse lymphoma.

Science 171:75-77(1971)

 

PubMed=30084848; DOI=10.1038/sdata.2018.157; PMCID=PMC6080492

Schuster H., Shao W.-G., Weiss T., Pedrioli P.G.A., Roth P., Weller M., Campbell D.S., Deutsch E.W., Moritz R.L., Planz O., Rammensee H.-G., Aebersold R., Caron E.

A tissue-based draft map of the murine MHC class I immunopeptidome.

Sci. Data 5:180157-180157(2018)