SK-NEP-1人肾母细胞瘤细胞 

SK-NEP-1/SK-NEP-1细胞系/SK-NEP-1细胞株/SK-NEP-1人肾母细胞瘤细胞

Cell line name SK-NEP-1

Synonyms SKNEP-1; SKNEP1; SKNEP

Accession CVCL_0631

Resource Identification Initiative To cite this cell line use: SK-NEP-1 (RRID:CVCL_0631)

Comments Problematic cell line: Misclassified. Originally thought to be a Wilm's tumor cell line but shown to be from an Ewing sarcoma (PubMed=17154184; PubMed=30924592).

Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).

Part of: COSMIC cell lines project.

Part of: MD Anderson Cell Lines Project.

From: Memorial Sloan Kettering Cancer Center; New York; USA.

Registration: Memorial Sloan Kettering Cancer Center Office of Technology Development; SK2008-052.

Population: Caucasian.

Microsatellite instability: Stable (MSS) (Sanger).

Omics: Deep exome analysis.

Omics: DNA methylation analysis.

Omics: Protein expression by reverse-phase protein arrays.

Omics: SNP array analysis.

Omics: Transcriptome analysis by microarray.

Omics: Transcriptome analysis by RNAseq.

Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.

PubMed=6244232

Williams R.D.

Human urologic cancer cell lines.

Invest. Urol. 17:359-363(1980)

 

PubMed=7459858

Rousset M., Zweibaum A., Fogh J.

Presence of glycogen and growth-related variations in 58 cultured human tumor cell lines of various tissue origins.

Cancer Res. 41:1165-1170(1981)

 

PubMed=3518877; DOI=10.3109/07357908609038260

Fogh J.

Human tumor lines for cancer research.

Cancer Invest. 4:157-184(1986)

 

PubMed=17154184; DOI=10.1002/pbc.21099

Smith M.A., Morton C.L., Phelps D.A., Girtman K., Neale G., Houghton P.J.

SK-NEP-1 and Rh1 are Ewing family tumor lines.

Pediatr. Blood Cancer 50:703-706(2008)

 

PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113

Bignell G.R., Greenman C.D., Davies H.R., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B.-Y., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F.-T., Campbell P.J., Futreal P.A., Stratton M.R.

Signatures of mutation and selection in the cancer genome.

Nature 463:893-898(2010)

 

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662

Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P., Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J., Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C., Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J., Haber D.A.

A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.

Cancer Res. 70:2158-2164(2010)

 

PubMed=25010205; DOI=10.1371/journal.pgen.1004475; PMCID=PMC4091782

Brohl A.S., Solomon D.A., Chang W., Wang J.-J., Song Y., Sindiri S., Patidar R., Hurd L., Chen L., Shern J.F., Liao H.-L., Wen X.-Y., Gerard J., Kim J.-S., Lopez Guerrero J.A., Machado I., Wai D.H., Picci P., Triche T.J., Horvai A.E., Miettinen M.M., Wei J.S., Catchpoole D., Llombart-Bosch A., Waldman T., Khan J.

The genomic landscape of the Ewing sarcoma family of tumors reveals recurrent STAG2 mutation.

PLoS Genet. 10:E1004475-E1004475(2014)

 

PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005; PMCID=PMC5501076

Li J., Zhao W., Akbani R., Liu W.-B., Ju Z.-L., Ling S.-Y., Vellano C.P., Roebuck P., Yu Q.-H., Eterovic A.K., Byers L.A., Davies M.A., Deng W.-L., Gopal Y.N.V., Chen G., von Euw E.M., Slamon D.J., Conklin D., Heymach J.V., Gazdar A.F., Minna J.D., Myers J.N., Lu Y.-L., Mills G.B., Liang H.

Characterization of human cancer cell lines by reverse-phase protein arrays.

Cancer Cell 31:225-239(2017)

 

PubMed=28489074; DOI=10.1038/ncomms15165; PMCID=PMC5436135

Sinha R., Winer A.G., Chevinsky M.S., Jakubowski C., Chen Y.-B., Dong Y.-Y., Tickoo S.K., Reuter V.E., Russo P., Coleman J.A., Sander C., Hsieh J.J.-D., Hakimi A.A.

Analysis of renal cancer cell lines from two major resources enables genomics-guided cell line selection.

Nat. Commun. 8:15165.1-15165.10(2017)

 

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675

Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.

An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.

Cancer Res. 79:1263-1273(2019)

 

PubMed=30924592; DOI=10.1002/pbc.27741

Pritchard-Jones K., Perotti D.

WARNING: G-401 and SK-NEP-1 cell lines are not Wilms tumor cell lines.

Pediatr. Blood Cancer 66:e27741.1-e27741.2(2019)

 

PubMed=31006967; DOI=10.1002/pbc.27769

Staege M.S.

Are EWSR1-FLI-positive cell lines from patients with other diagnoses than Ewing sarcoma really Ewing sarcoma cell lines?

Pediatr. Blood Cancer 66:e27769.1-e27769.2(2019)