TE-12人食管癌细胞
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TE-12人食管癌细胞

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      T25

    Cell line name TE-12

    Synonyms TE12

    Accession CVCL_1762

    Resource Identification Initiative To cite this cell line use: TE-12 (RRID:CVCL_1762)

    Comments Problematic cell line: Contaminated. TE-2, TE-3, TE-7, TE-12 and TE-13 have been shown to be identical (PubMed=17804709; PubMed=20143388).

    Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).

    Part of: COSMIC cell lines project.

    Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00273.

    Population: Japanese.

    Microsatellite instability: Stable (MSS) (Sanger).

    Omics: Deep exome analysis.

    Omics: Deep quantitative proteome analysis.

    Omics: DNA methylation analysis.

    Omics: SNP array analysis.

    Omics: Transcriptome analysis by microarray.

    Genome ancestry Source: PubMed=30894373

     

    Origin % genome

    African 0

    Native American 0.13

    East Asian, North 76.19

    East Asian, South 22.61

    South Asian 0.51

    European, North 0.56

    European, South 0

    Disease Esophageal squamous cell carcinoma (NCIt: C4024)

    Squamous cell carcinoma of the esophagus (ORDO: Orphanet_99977)

    Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)

    Originate from same individual CVCL_4455 ! TE-2

    CVCL_9971 ! TE-3

    CVCL_9972 ! TE-7

    CVCL_4463 ! TE-13

    Sex of cell Male

    Category Cancer cell line

    STR profile Source(s): Cosmic-CLP=946356

     

    Markers:

    Amelogenin X,Y

    CSF1PO 11

    D5S818 11

    D7S820 10,13

    D13S317 12

    D16S539 9,10

    TH01 9

    TPOX 8

    vWA 16,17

     

    PubMed=8509434; DOI=10.1007/BF01215923

    Nishihira T., Hashimoto Y., Katayama M., Mori S., Kuroki T.

    Molecular and cellular features of esophageal cancer cells.

    J. Cancer Res. Clin. Oncol. 119:441-449(1993)

     

    PubMed=9290701; DOI=10.1002/(SICI)1098-2744(199708)19:4<243::AID-MC5>3.0.CO;2-D

    Jia L.-Q., Osada M., Ishioka C., Gamo M., Ikawa S., Suzuki T., Shimodaira H., Niitani T., Kudo T., Akiyama M., Kimura N., Matsuo M., Mizusawa H., Tanaka N., Koyama H., Namba M., Kanamaru R., Kuroki T.

    Screening the p53 status of human cell lines using a yeast functional assay.

    Mol. Carcinog. 19:243-253(1997)

     

    PubMed=17804709; DOI=10.1158/0008-5472.CAN-07-2064

    Boonstra J.J., van der Velden A.W., Beerens E.C.W., van Marion R., Morita-Fujimura Y., Matsui Y., Nishihira T., Tselepis C., Hainaut P., Lowe A.W., Beverloo H.B., van Dekken H., Tilanus H.W., Dinjens W.N.M.

    Mistaken identity of widely used esophageal adenocarcinoma cell line TE-7.

    Cancer Res. 67:7996-8001(2007)

     

    PubMed=20143388; DOI=10.1002/ijc.25242

    Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I.

    Check your cultures! A list of cross-contaminated or misidentified cell lines.

    Int. J. Cancer 127:1-8(2010)

     

    PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113

    Bignell G.R., Greenman C.D., Davies H.R., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B.-Y., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F.-T., Campbell P.J., Futreal P.A., Stratton M.R.

    Signatures of mutation and selection in the cancer genome.

    Nature 463:893-898(2010)

     

    PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469

    Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X.-M., Egan R.K., Liu Q.-S., MT., Mitropoulos X., Richardson L., Wang J.-H., Zhang T.-H., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.

    A landscape of pharmacogenomic interactions in cancer.

    Cell 166:740-754(2016)

     

    PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675

    Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.

    An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.

    Cancer Res. 79:1263-1273(2019)

     

    PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010; PMCID=PMC9387775

    Goncalves E., Poulos R.C., Cai Z.-X., Barthorpe S., Manda S.S., Lucas N., Beck A., Bucio-Noble D., Dausmann M., Hall C., Hecker M., Koh J., Lightfoot H., Mahboob S., Mali I., Morris J., Richardson L., Seneviratne A.J., Shepherd R., Sykes E., Thomas F., Valentini S., Williams S.G., Wu Y.-X., Xavier D., MacKenzie K.L., Hains P.G., Tully B., Robinson P.J., Zhong Q., Garnett M.J., Reddel R.R.

    Pan-cancer proteomic map of 949 human cell lines.

    Cancer Cell 40:835-849.e8(2022)

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