NT2-D1(NTERA-2 clone D1)人睾丸癌细胞

NTERA-2 cl.D1/NTERA-2 cl.D1细胞系/NTERA-2 cl.D1细胞株/NTERA-2 cl.D1人睾丸癌细胞

Cell line name NT2-D1

Synonyms NT2/D1; NT2D1; Nt2D1; NTERA-2 clone D1; NTERA2-cloneD1; NTERA-2 cl.D1; NTera2 cl.D1; NTERA-2cl.D1; NTera 2/cl.D1; NTERA2CLD1; NTERA-2/D1; NTera2/D1; NTERA2-D1; NTera-2D1; Ntera2/D1; NTERA2/D1; NTERA2D1; NTera2D1; Tera

Accession CVCL_3407

Resource Identification Initiative To cite this cell line use: NT2-D1 (RRID:CVCL_3407)

Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).

Part of: COSMIC cell lines project.

Part of: ENCODE project common cell types; tier 3.

Population: Caucasian.

Microsatellite instability: Stable (MSS) (Sanger).

Omics: Deep exome analysis.

Omics: Deep quantitative proteome analysis.

Omics: DNA methylation analysis.

Omics: H3K9ac ChIP-seq epigenome analysis.

Omics: Transcriptome analysis by microarray.

Misspelling: NTERA-S-cl-D1; ArrayExpress=E-MTAB-783; CLO=CLO_0037150; Cosmic=1995598.

Misspelling: NTL-D1; Cosmic=2077191.

Misspelling: NT2101; Cosmic=2163756; PubMed=24812411.

Derived from site: Metastatic; Lung; UBERON=UBERON_0002048.

PubMed=6144603; DOI=10.1016/0012-1606(84)90316-6

Andrews P.W.

Retinoic acid induces neuronal differentiation of a cloned human embryonal carcinoma cell line in vitro.

Dev. Biol. 103:285-293(1984)

 

PubMed=6694356

Andrews P.W., Damjanov I., Simon D., Banting G.S., Carlin C.R., Dracopoli N.C., Fogh J.

Pluripotent embryonal carcinoma clones derived from the human teratocarcinoma cell line Tera-2. Differentiation in vivo and in vitro.

Lab. Invest. 50:147-162(1984)

 

PubMed=3293662; DOI=10.1016/0304-419X(88)90003-0

Andrews P.W.

Human teratocarcinomas.

Biochim. Biophys. Acta 948:17-36(1988)

 

PubMed=8242627

Timmer-Bosscha H., Timmer A., Meijer C., de Vries E.G.E., de Jong B., Oosterhuis J.W., Mulder N.H.

cis-diamminedichloroplatinum(ii) resistance in vitro and in vivo in human embryonal carcinoma cells.

Cancer Res. 53:5707-5713(1993)

 

PubMed=8411264; DOI=10.1002/jnr.490350603

Pleasure S.J., Lee V.M.-Y.

NTera 2 cells: a human cell line which displays characteristics expected of a human committed neuronal progenitor cell.

J. Neurosci. Res. 35:585-602(1993)

 

PubMed=23325432; DOI=10.1101/gr.147942.112; PMCID=PMC3589544

Varley K.E., Gertz J., Bowling K.M., Parker S.L., Reddy T.E., Pauli-Behn F., Cross M.K., Williams B.A., Stamatoyannopoulos J.A., Crawford G.E., Absher D.M., Wold B.J., Myers R.M.

Dynamic DNA methylation across diverse human cell lines and tissues.

Genome Res. 23:555-567(2013)

 

PubMed=24812411; DOI=10.1158/1078-0432.CCR-13-2868

Feldman D.R., Iyer G., Van Alstine L., Patil S., Al-Ahmadie H., Reuter V.E., Bosl G.J., Chaganti R.S.K., Solit D.B.

Presence of somatic mutations within PIK3CA, AKT, RAS, and FGFR3 but not BRAF in cisplatin-resistant germ cell tumors.

Clin. Cancer Res. 20:3712-3720(2014)

 

PubMed=25802994; DOI=10.1177/026119291504300105

Jasnic-Savovic J., Klajn A., Milivojevic M., Mojsin M., Nikcevic G.

Human embryonal carcinoma cells in serum-free conditions as an in vitro model system of neural differentiation.

Altern. Lab. Anim. 43:9-18(2015)

 

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469

Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X.-M., Egan R.K., Liu Q.-S., Miro T., Mitropoulos X., Richardson L., Wang J.-H., Zhang T.-H., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.

A landscape of pharmacogenomic interactions in cancer.

Cell 166:740-754(2016)

 

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675

Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.

An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.

Cancer Res. 79:1263-1273(2019)

 

PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010; PMCID=PMC9387775

Goncalves E., Poulos R.C., Cai Z.-X., Barthorpe S., Manda S.S., Lucas N., Beck A., Bucio-Noble D., Dausmann M., Hall C., Hecker M., Koh J., Lightfoot H., Mahboob S., Mali I., Morris J., Richardson L., Seneviratne A.J., Shepherd R., Sykes E., Thomas F., Valentini S., Williams S.G., Wu Y.-X., Xavier D., MacKenzie K.L., Hains P.G., Tully B., Robinson P.J., Zhong Q., Garnett M.J., Reddel R.R.

Pan-cancer proteomic map of 949 human cell lines.

Cancer Cell 40:835-849.e8(2022)