NCI-H526人小细胞肺癌细胞

NCI-H526细胞系；H526细胞株；NCI-H526细胞；H526细胞；NCI-H526小细胞肺癌细胞

Cell line name NCI-H526

Synonyms H526; H-526; NCIH526

Accession CVCL_1569

Resource Identification Initiative To cite this cell line use: NCI-H526 (RRID:CVCL_1569)

Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).

Part of: COSMIC cell lines project.

Population: Caucasian.

Microsatellite instability: Instable (MSI-low) (Sanger).

Omics: Array-based CGH.

Omics: Deep exome analysis.

Omics: Deep proteome analysis.

Omics: Deep quantitative proteome analysis.

Omics: DNA methylation analysis.

Omics: miRNA expression profiling.

Omics: Protein expression by reverse-phase protein arrays.

Omics: SNP array analysis.

Omics: Transcriptome analysis by microarray.

Omics: Transcriptome analysis by RNAseq.

Derived from site: Metastatic; Bone marrow; UBERON=UBERON_0002371.

PubMed=1312696

D'Amico D., Carbone D.P., Mitsudomi T., Nau M.M., Fedorko J., Russell E., Johnson B., Buchhagen D.L., Bodner S.M., Phelps R.M., Gazdar A.F., Minna J.D.

High frequency of somatically acquired p53 mutations in small-cell lung cancer cell lines and tumors.

Oncogene 7:339-346(1992)

 

PubMed=1320893; DOI=10.1159/000163712

Verbeeck M.A.E., Elands J.P.M., de Leij L.F.M.H., Buys C.H.C.M., Carney D.N., Bepler G., Roebroek A.J.M., van de Ven W.J.M., Burbach J.P.H.

Expression of the vasopressin and gastrin-releasing peptide genes in small cell lung carcinoma cell lines.

Pathobiology 60:136-142(1992)

 

PubMed=1565469

Bodner S.M., Minna J.D., Jensen S.M., D'Amico D., Carbone D.P., Mitsudomi T., Fedorko J., Buchhagen D.L., Nau M.M., Gazdar A.F., Linnoila R.I.

Expression of mutant p53 proteins in lung cancer correlates with the class of p53 gene mutation.

Oncogene 7:743-749(1992)

 

PubMed=8806092; DOI=10.1002/jcb.240630505

Phelps R.M., Johnson B.E., Ihde D.C., Gazdar A.F., Carbone D.P., McClintock P.R., Linnoila R.I., Matthews M.J., Bunn P.A. Jr., Carney D.N., Minna J.D., Mulshine J.L.

NCI-Navy Medical Oncology Branch cell line data base.

J. Cell. Biochem. Suppl. 24:32-91(1996)

 

PubMed=8806103; DOI=10.1002/jcb.240630516

Johnson B.E., Russell E., Simmons A.M., Phelps R.M., Steinberg S.M., Ihde D.C., Gazdar A.F.

MYC family DNA amplification in 126 tumor cell lines from patients with small cell lung cancer.

J. Cell. Biochem. Suppl. 24:210-217(1996)

 

PubMed=10037197

Tang X.X., Brodeur G.M., Campling B.G., Ikegaki N.

Coexpression of transcripts encoding EPHB receptor protein tyrosine kinases and their ephrin-B ligands in human small cell lung carcinoma.

Clin. Cancer Res. 5:455-460(1999)

 

PubMed=11005564; DOI=10.1038/sj.neo.7900094; PMCID=PMC1550293

Kohno T., Sato T., Takakura S., Takei K., Inoue K., Nishioka M., Yokota J.

Mutation and expression of the DCC gene in human lung cancer.

Neoplasia 2:300-305(2000)

 

PubMed=11030152; DOI=10.1038/sj.onc.1203815

Modi S., Kubo A., Oie H.K., Coxon A.B., Rehmatulla A., Kaye F.J.

Protein expression of the RB-related gene family and SV40 large T antigen in mesothelioma and lung cancer.

Oncogene 19:4632-4639(2000)

 

PubMed=17426248; DOI=10.1158/1541-7786.MCR-06-0367

Olejniczak E.T., Van Sant C., Anderson M.G., Wang G., Tahir S.K., Sauter G., Lesniewski R., Semizarov D.

Integrative genomic analysis of small-cell lung carcinoma reveals correlates of sensitivity to bcl-2 antagonists and uncovers novel chromosomal gains.

Mol. Cancer Res. 5:331-339(2007)