HUCCT1人胆管癌细胞

HuCCT1细胞；HuCC-T1人胆管上皮癌细胞Cell line name HuCC-T1

Synonyms HuCCT-1; HUCCT-1; HUCC-T1; HUCCT1; HuCCT1

Accession CVCL_0324

Resource Identification Initiative To cite this cell line use: HuCC-T1 (RRID:CVCL_0324)

Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).

Part of: COSMIC cell lines project.

Part of: TCGA-110-CL cell line panel.

Population: Japanese.

Doubling time: ~55 hours (Note=At 10th passage in RPMI + 10% FBS), ~74 hours (Note=At 25th passage in RPMI + 0.2% LA) (PubMed=2544546).

Microsatellite instability: Stable (MSS) (Sanger).

Omics: Deep exome analysis.

Omics: Deep quantitative proteome analysis.

Omics: DNA methylation analysis.

Omics: HLA class I peptidome analysis by proteomics.

Omics: SNP array analysis.

Omics: Transcriptome analysis by microarray.

Omics: Transcriptome analysis by RNAseq.

Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.

Markers:

Amelogenin X,Y

CSF1PO 11,12

D2S1338 17,18

D3S1358 15

D5S818 12,13

D6S1043 13

D7S820 10,11

D8S1179 10

D12S391 18,20

D13S317 11,13

D16S539 9,11,12 (PubMed=25877200)

11,12 (CLS=300469; Cosmic-CLP=907069; JCRB=JCRB0425; RCB=RCB1960; TKG=TKG 0389)

D18S51 13

D19S433 13

D21S11 31

FGA 20,23

Penta D 10

Penta E 15,18

TH01 7,10

TPOX 8

vWA 18

PubMed=2544546; DOI=10.1007/BF02623562

Miyagiwa M., Ichida T., Tokiwa T., Sato J., Sasaki H.

A new human cholangiocellular carcinoma cell line (HuCC-T1) producing carbohydrate antigen 19/9 in serum-free medium.

In Vitro Cell. Dev. Biol. 25:503-510(1989)

 

DOI=10.11418/jtca1981.16.3_173

Mihara K., Miyazaki M., Fushimi K., Tsuji T., Inoue Y., Fukaya K.-i., Ohashi R., Namba M.

The p53 gene status and other cellular characteristics of human cell lines maintained in our laboratory.

Tissue Cult. Res. Commun. 16:173-178(1997)

 

PubMed=9290701; DOI=10.1002/(SICI)1098-2744(199708)19:4<243::AID-MC5>3.0.CO;2-D

Jia L.-Q., Osada M., Ishioka C., Gamo M., Ikawa S., Suzuki T., Shimodaira H., Niitani T., Kudo T., Akiyama M., Kimura N., Matsuo M., Mizusawa H., Tanaka N., Koyama H., Namba M., Kanamaru R., Kuroki T.

Screening the p53 status of human cell lines using a yeast functional assay.

Mol. Carcinog. 19:243-253(1997)

 

PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113

Bignell G.R., Greenman C.D., Davies H.R., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B.-Y., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F.-T., Campbell P.J., Futreal P.A., Stratton M.R.

Signatures of mutation and selection in the cancer genome.

Nature 463:893-898(2010)

 

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662

Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P., Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J., Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C., Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J., Haber D.A.

A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.

Cancer Res. 70:2158-2164(2010)

 

PubMed=21451941; DOI=10.1007/s00534-011-0376-7

Sato J., Kimura T., Saito T., Anazawa T., Kenjo A., Sato Y., Tsuchiya T., Gotoh M.

Gene expression analysis for predicting gemcitabine resistance in human cholangiocarcinoma.

J. Hepatobiliary Pancreat. Sci. 18:700-711(2011)

 

PubMed=21687941; DOI=10.3892/ijo.2011.1087

Kamigaki M., Sasaki T., Serikawa M., Inoue M., Kobayashi K., Itsuki H., Minami T., Yukutake M., Okazaki A., Ishigaki T., Ishii Y., Kosaka K., Chayama K.

Statins induce apoptosis and inhibit proliferation in cholangiocarcinoma cells.

Int. J. Oncol. 39:561-568(2011)

 

PubMed=22460905; DOI=10.1038/nature11003; PMCID=PMC3320027

Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.-Y.K., Yu J.-J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L.E., Winckler W., Reich M., Li N.-X., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M.L., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.

Nature 483:603-607(2012)

 

CLPUB00275

Zach S., Birgin E., Ruckert F.

Primary cholangiocellular carcinoma cell lines.

J. Stem Cell Res. Transplant. 2:1013-1013(2015)

 

PubMed=25877200; DOI=10.1038/nature14397