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T25
CHO-S、CHO-S、CHO-S细胞、CHO-S细胞、CHO-S中国仓鼠卵巢细胞
Cell line name CHO-S
Synonyms CHO-s; CHOS
Accession CVCL_7183
Resource Identification Initiative To cite this cell line use: CHO-S (RRID:CVCL_7183)
Comments Omics: Deep proteome analysis.
Omics: Genome sequenced.
Omics: miRNA expression profiling.
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Cell type: Epithelial cell of ovary; CL=CL_2000064.
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_0213 (CHO)
Children:
CVCL_B6JC (C-HAlb) CVCL_A9NY (CHO C1s-/-) CVCL_VP59 (CHO MGAT1-)
CVCL_4386 (CHO-AA8) CVCL_D264 (CHO-AUXB1) CVCL_5A30 (CHO-AUXB3)
CVCL_M722 (CHO-AUXE29) CVCL_WJ93 (CHO-S FUT8-/-) CVCL_A0AT (CHO-S r34.1 (clone D8))
CVCL_5A26 (CHO-S/C0101) CVCL_A0TS (CHO-S/H9C2) CVCL_XF07 (CHO-S/K70E10-1D6)
CVCL_0F81 (CHO-tsH1) CVCL_Y012 (CHOS-XE) CVCL_5J31 (ExpiCHO-S)
CVCL_D604 (FreeStyle CHO-S) CVCL_JG26 (hTf/CHO-S #17) CVCL_JG28 (hTf/CHO-S #29)
CVCL_RN06 (PDIS-14) CVCL_RN10 (PDIS-9) CVCL_EG61 (pREP4 cont/CHO-S #5)
CVCL_A0AU (UCSC.PG128.CHO.S.F4)
Sex of cell Female
Age at sampling Adult
Category Spontaneously immortalized cell line
PubMed=4585080; DOI=10.1016/S0091-679X(08)60052-7
Thompson L.H., Baker R.M.
Isolation of mutants of cultured mammalian cells.
Methods Cell Biol. 6:209-281(1973)
PubMed=837451; DOI=10.1016/0092-8674(77)90224-0
Konrad M.W., Storrie B., Glaser D.A., Thompson L.H.
Clonal variation in colony morphology and growth of CHO cells cultured on agar.
Cell 10:305-312(1977)
DOI=10.3390/pr1030296
Wurm F.M.
CHO quasispecies -- implications for manufacturing processes.
Processes 1:296-311(2013)
PubMed=23873082; DOI=10.1038/nbt.2624
Lewis N.E., Liu X., Li Y.-X., Nagarajan H., Yerganian G., O'Brien E., Bordbar A., Roth A.M., Rosenbloom J., Bian C., Xie M., Chen W.-B., Li N., Baycin-Hizal D., Latif H., Forster J., Betenbaugh M.J., Famili I., Xu X., Wang J., Palsson B.O.
Genomic landscapes of Chinese hamster ovary cell lines as revealed by the Cricetulus griseus draft genome.
Nat. Biotechnol. 31:759-765(2013)
PubMed=26993211; DOI=10.1016/j.jbiotec.2016.03.022
Klanert G., Jadhav V., Shanmukam V., Diendorfer A.B., Karbiener M., Scheideler M., Hernandez-Bort J.A., Grillari J., Hackl M., Borth N.
A signature of 12 microRNAs is robustly associated with growth rate in a variety of CHO cell lines.
J. Biotechnol. 235:150-161(2016)
DOI=10.3390/pr5020020
Wurm F.M., Wurm M.J.
Cloning of CHO cells, productivity and genetic stability -- a discussion.
Processes 5:20.1-20.13(2017)
PubMed=28876938; DOI=10.1021/acs.jproteome.7b00382
Heffner K.M., Baycin-Hizal D., Yerganian G., Kumar A., Can O., O'Meally R.N., Cole R.N., Chaerkady R., Wu H., Bowen M.A., Betenbaugh M.J.
Lessons from the hamster: Cricetulus griseus tissue and CHO cell line proteome comparison.
J. Proteome Res. 16:3672-3687(2017)
PubMed=32985598; DOI=10.1038/s41598-020-72959-8; PMCID=PMC7522264
Heffner K.M., Baycin-Hizal D., Majewska N.I., Kumar S., Dhara V.G., Zhu J., Bowen M.A., Hatton D., Yerganian G., Yerganian A., O'Meally R.N., Cole R.N., Betenbaugh M.J.
Expanded Chinese hamster organ and cell line proteomics profiling reveals tissue-specific functionalities.
Sci. Rep. 10:15841-15841(2020)
PubMed=34050613; DOI=10.1002/biot.202100165
Wurm M.J., Wurm F.M.
Naming CHO cells for bio-manufacturing: genome plasticity and variant phenotypes of cell populations in bioreactors question the relevance of old names.
Biotechnol. J. 16:e2100165.1-e2100165.13(2021)
PubMed=36610518; DOI=10.1016/j.ymben.2022.12.009; PMCID=PMC11132536
Kotidis P., Donini R., Arnsdorf J., Hansen A.H., Voldborg B.G.R., Chiang A.W.-T., Haslam S.M., Betenbaugh M.J., Jimenez del Val I., Lewis N.E., Krambeck F.J., Kontoravdi C.
CHOGlycoNET: comprehensive glycosylation reaction network for CHO cells.
Metab. Eng. 76:87-96(2023)
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文献和实验*发表【中文论文】请标注:由上海酶研生物科技有限公司提供;
*发表【英文论文】请标注:From Shanghai EK-Bioscience Biotechnology Co., Ltd.









