P19

P19/P19细胞系/P19细胞株/P19小鼠睾丸畸胎瘤细胞

Cell line name P19

Synonyms P-19

Accession CVCL_2153

Resource Identification Initiative To cite this cell line use: P19 (RRID:CVCL_2153)

Comments Doubling time: ~2-3 days (DSMZ=ACC-316).

Caution: There seem to be 3 distinct cell lines which were assigned NCBI_Iran catalog number C422.

Derived from site: In situ; Whole embryo; UBERON=UBERON_0000922.

Cell type: Epithelial cell; CL=CL_0000066.

Disease Mouse teratocarcinoma (NCIt: C129859)

Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)

Breed/subspecies: C3H/He.

Hierarchy Children:

CVCL_L988 (P19C6) CVCL_L981 (P19CL6) CVCL_D6NC (P19S11)

CVCL_D6ND (P19S18) CVCL_D6NE (P19S8)

Sex of cell Male

Age at sampling 7FD

Category Cancer cell line

STR profile Source(s): PubMed=31220119

 

Markers:

Mouse STR 1-1 10

Mouse STR 1-2 16,17

Mouse STR 2-1 9

Mouse STR 3-2 14

Mouse STR 4-2 13,21.3

Mouse STR 5-5 14

Mouse STR 6-4 18

Mouse STR 6-7 12

Mouse STR 7-1 26

Mouse STR 8-1 16

Mouse STR 11-2 16

Mouse STR 12-1 16

Mouse STR 13-1 17

Mouse STR 15-3 26.3

Mouse STR 17-2 15

Mouse STR 18-3 16,17

Mouse STR 19-2 12,14

Mouse STR X-1 26

 

Run an STR similarity search on this cell line

Publications

PubMed=7056443; DOI=10.1016/0012-1606(82)90338-4

McBurney M.W., Rogers B.J.

Isolation of male embryonal carcinoma cells and their chromosome replication patterns.

Dev. Biol. 89:503-508(1982)

 

PubMed=7107698; DOI=10.1083/jcb.94.2.253; PMCID=PMC2112882

Jones-Villeneuve E.M., McBurney M.W., Rogers K.A., Kalnins V.I.

Retinoic acid induces embryonal carcinoma cells to differentiate into neurons and glial cells.

J. Cell Biol. 94:253-262(1982)

 

PubMed=8507558

McBurney M.W.

P19 embryonal carcinoma cells.

Int. J. Dev. Biol. 37:135-140(1993)

 

PubMed=8069455; DOI=10.1007/BF02631450

Fukuchi K.-i., Hearn M.G., Deeb S.S., Smith A.C., Ngoc Thao D., Miyazaki J.-i., Bothwell M., Martin G.M.

Activity assays of nine heterogeneous promoters in neural and other cultured cells.

In Vitro Cell. Dev. Biol. Anim. 30:300-305(1994)

 

PubMed=12757864; DOI=10.1016/S0008-6363(02)00771-X

van der Heyden M.A.G., Defize L.H.K.

Twenty one years of P19 cells: what an embryonal carcinoma cell line taught us about cardiomyocyte differentiation.

Cardiovasc. Res. 58:292-302(2003)

 

PubMed=31220119; DOI=10.1371/journal.pone.0218412; PMCID=PMC6586308

Almeida J.L., Dakic A., Kindig K., Kone M., Letham D.L.D., Langdon S., Peat R., Holding-Pillai J., Hall E.M., Ladd M., Shaffer M.D., Berg H., Li J.-L., Wigger G., Lund S., Steffen C.R., Fransway B.B., Geraghty B., Natoli M., Bauer B.A., Gollin S.M., Lewis D.W., Reid Y.A.

Interlaboratory study to validate a STR profiling method for intraspecies identification of mouse cell lines.

PLoS ONE 14:E0218412-E0218412(2019)