MNT-1

MNT-1/MNT-1细胞系/MNT-1细胞株/MNT-1人黑色素瘤细胞

Cell line name MNT-1

Synonyms MNT1; MNT

Accession CVCL_5624

Resource Identification Initiative To cite this cell line use: MNT-1 (RRID:CVCL_5624)

Comments Characteristics: Highly pigmented.

Virology: Susceptible to infection by human metapneumovirus (MNPV) (PubMed=28940687).

Omics: Exosome proteome analysis.

Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.

Disease Melanoma (NCIt: C3224)

Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)

Originate from same individual CVCL_5625 ! MNT-3

Sex of cell Sex unspecified

Age at sampling Age unspecified

Category Cancer cell line

STR profile Source(s): ATCC=CRL-3450

 

Markers:

Amelogenin X

CSF1PO 10

D5S818 13

D7S820 9

D13S317 11

D16S539 10

TH01 6,9

TPOX 8,10

vWA 16,18

 

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Publications

PubMed=1701342

Nistico P., Tecce R., Giacomini P., Cavallari A., D'Agnano I., Fisher P.B., Natali P.G.

Effect of recombinant human leukocyte, fibroblast, and immune interferons on expression of class I and II major histocompatibility complex and invariant chain in early passage human melanoma cells.

Cancer Res. 50:7422-7429(1990)

 

PubMed=1706743; DOI=10.1111/1523-1747.ep12470092

Cuomo M., Nicotra M.R., Apollonj C., Fraioli R., Giacomini P., Natali P.G.

Production and characterization of the murine monoclonal antibody 2G10 to a human T4-tyrosinase epitope.

J. Invest. Dermatol. 96:446-451(1991)

 

PubMed=11266471; DOI=10.1083/jcb.152.4.809; PMCID=PMC2195785

Raposo G., Tenza D., Murphy D.M., Berson J.F., Marks M.S.

Distinct protein sorting and localization to premelanosomes, melanosomes, and lysosomes in pigmented melanocytic cells.

J. Cell Biol. 152:809-824(2001)

 

PubMed=12417263; DOI=10.1016/S0006-2952(02)01353-9

De Marco F., Perluigi M., Marcante M.L., Coccia R., Foppoli C., Blarzino C., Rosei M.A.

Cytotoxicity of dopamine-derived tetrahydroisoquinolines on melanoma cells.

Biochem. Pharmacol. 64:1503-1512(2002)

 

PubMed=25950383; DOI=10.1111/pcmr.12380

Lazar I., Clement E., Ducoux-Petit M., Denat L., Soldan V., Dauvillier S., Balor S., Burlet-Schiltz O., Larue L., Muller C., Nieto L.

Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines.

Pigment Cell Melanoma Res. 28:464-475(2015)

 

PubMed=28940687; DOI=10.1111/1348-0421.12542

Sato K., Watanabe O., Ohmiya S., Chiba F., Suzuki A., Okamoto M., Younghuang J., Hata A., Nonaka H., Kitaoka S., Nagai Y., Kawamura K., Hayashi M., Kumaki S., Suzuki T., Kawakami K., Nishimura H.

Efficient isolation of human metapneumovirus using MNT-1, a human malignant melanoma cell line with early and distinct cytopathic effects.

Microbiol. Immunol. 61:497-506(2017)