SKNO-1

SKNO-1/SKNO-1细胞系/SKNO-1细胞株/SKNO-1人急性髓系白血病细胞

Cell line name SKNO-1

Synonyms Skno-1; SKNO1

Accession CVCL_2196

Resource Identification Initiative To cite this cell line use: SKNO-1 (RRID:CVCL_2196)

Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).

Part of: LL-100 blood cancer cell line panel.

Population: Japanese.

Characteristics: CSF2 dependent.

Doubling time: 48-72 hours (PubMed=7772516); 24 hours (PubMed=25984343); ~35-50 hours (DSMZ=ACC-690); ~38 hours (Note=Lot 06112012), 52-57 hours (Note=Lot 02032016) (JCRB=JCRB1170).

Omics: Deep exome analysis.

Omics: shRNA library screening.

Omics: Transcriptome analysis by RNAseq.

Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.

PubMed=11753612; DOI=10.1038/sj.leu.2402318

Xiao Z.-X., Greaves M.F., Buffler P.A., Smith M.T., Segal M.R., Dicks B.M., Wiencke J.K., Wiemels J.L.

Molecular characterization of genomic AML1-ETO fusions in childhood leukemia.

Leukemia 15:1906-1913(2001)

 

PubMed=15843827; DOI=10.1038/sj.leu.2403749

Andersson A., Eden P., Lindgren D., Nilsson J., Lassen C., Heldrup J., Fontes M., Borg A., Mitelman F., Johansson B., Hoglund M., Fioretos T.

Gene expression profiling of leukemic cell lines reveals conserved molecular signatures among subtypes with specific genetic aberrations.

Leukemia 19:1042-1050(2005)

 

PubMed=18385756; DOI=10.1038/leu.2008.61

Becker H., Pfeifer D., Duque-Afonso J., Nimer S.D., Veelken H., Schwabe M., Lubbert M.

Two cell lines of t(8;21) acute myeloid leukemia with activating KIT exon 17 mutation: models for the 'second hit' hypothesis.

Leukemia 22:1792-1794(2008)

 

PubMed=25984343; DOI=10.1038/sdata.2014.35; PMCID=PMC4432652

Cowley G.S., Weir B.A., Vazquez F., Tamayo P., Scott J.A., Rusin S., East-Seletsky A., Ali L.D., Gerath W.F.J., Pantel S.E., Lizotte P.H., Jiang G.-Z., Hsiao J., Tsherniak A., Dwinell E., Aoyama S., Okamoto M., Harrington W., Gelfand E.T., Green T.M., Tomko M.J., Gopal S., Wong T.C., Li H.-B., Howell S., Stransky N., Liefeld T., Jang D., Bistline J., Meyers B.H., Armstrong S.A., Anderson K.C., Stegmaier K., Reich M., Pellman D., Boehm J.S., Mesirov J.P., Golub T.R., Root D.E., Hahn W.C.

Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies.

Sci. Data 1:140035-140035(2014)

 

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675

Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.

An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.

Cancer Res. 79:1263-1273(2019)