IOSE80

IOSE-80/IOSE-80细胞系/IOSE-80细胞株/IOSE-80人正常卵巢上皮细胞

Cell line name IOSE-80

Synonyms IOSE 80; IOSE80; NFHIOSE-80; IOSE80UBC; IOSE-Van; IOSE-VAN

Accession CVCL_5546

Resource Identification Initiative To cite this cell line use: IOSE-80 (RRID:CVCL_5546)

Comments From: Canadian Ovarian Tissue Bank, University of British Columbia; Vancouver; Canada.

Doubling time: 26.2 hours (PubMed=10329039).

Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).

Derived from site: In situ; Ovary, surface epithelium; UBERON=UBERON_0001304.

Cell type: Epithelial cell of ovary; CL=CL_2000064.

Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)

Hierarchy Children:

CVCL_5547 (IOSE-80PC) CVCL_5548 (IOSE-80RZ) CVCL_2G68 (T80)

Sex of cell Female

Age at sampling Age unspecified

Category Transformed cell line

Publications

PubMed=1326894; DOI=10.1016/S0002-9378(11)91579-8

Maines-Bandiera S.L., Kruk P.A., Auersperg N.

Simian virus 40-transformed human ovarian surface epithelial cells escape normal growth controls but retain morphogenetic responses to extracellular matrix.

Am. J. Obstet. Gynecol. 167:729-735(1992)

 

PubMed=7967506

Auersperg N., Maines-Bandiera S.L., Dyck H.G., Kruk P.A.

Characterization of cultured human ovarian surface epithelial cells: phenotypic plasticity and premalignant changes.

Lab. Invest. 71:510-518(1994)

 

PubMed=10329039; DOI=10.1006/gyno.1999.5348

Kruk P.A., Godwin A.K., Hamilton T.C., Auersperg N.

Telomeric instability and reduced proliferative potential in ovarian surface epithelial cells from women with a family history of ovarian cancer.

Gynecol. Oncol. 73:229-236(1999)

 

DOI=10.5282/edoc.3898

Euer N.I.

Identification of target genes for the therapy and diagnosis of ovarian carcinoma.

Thesis PhD (2005); Ludwig Maximilians University of Munich; Munich; Germany

 

PubMed=15706405; DOI=10.3892/or.13.3.375

Euer N.I., Kaul S., Deissler H., Mobus V.J., Zeillinger R., Weidle U.H.

Identification of L1CAM, Jagged2 and neuromedin U as ovarian cancer-associated antigens.

Oncol. Rep. 13:375-387(2005)

 

PubMed=15947112; DOI=10.1677/erc.1.00896

Choi J.-H., Choi K.-C., Auersperg N., Leung P.C.K.

Gonadotropins upregulate the epidermal growth factor receptor through activation of mitogen-activated protein kinases and phosphatidyl-inositol-3-kinase in human ovarian surface epithelial cells.

Endocr. Relat. Cancer 12:407-421(2005)

 

PubMed=19926575; DOI=10.1309/AJCPTK87EMMIKPFS; PMCID=PMC3040237

DeRycke M.S., Andersen J.D., Harrington K.M., Pambuccian S.E., Kalloger S.E., Boylan K.L.M., Argenta P.A., Skubitz A.P.N.

S100A1 expression in ovarian and endometrial endometrioid carcinomas is a prognostic indicator of relapse-free survival.

Am. J. Clin. Pathol. 132:846-856(2009)

 

PubMed=23415752; DOI=10.1016/j.molonc.2012.12.007; PMCID=PMC4106023

Stordal B., Timms K., Farrelly A., Gallagher D., Busschots S., Renaud M., Thery J., Williams D., Potter J., Tran T., Korpanty G., Cremona M., Carey M.S., Li J., Li Y., Aslan O., O'Leary J.J., Mills G.B., Hennessy B.T.

BRCA1/2 mutation analysis in 41 ovarian cell lines reveals only one functionally deleterious BRCA1 mutation.

Mol. Oncol. 7:567-579(2013)