NUGC-3细胞

NUGC-3细胞NUGC-3人胃癌细胞

Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: COSMIC cell lines project.
Part of: JFCR45 cancer cell line panel.
Part of: MD Anderson Cell Lines Project.
Population: Japanese.
Doubling time: 38.2 hours (PubMed=3172586); 29 hours (PubMed=29435981); ~26 hours (Note=Lot 06062005), 28-45 hours (Note=Lot 04272009), ~32 hours (Note=Lot 11042011), ~28 hours (Note=Lot 02262016), ~1 day (Note=Lot 11162017) (JCRB=JCRB0822).
Microsatellite instability: Instable (MSI-high) (PubMed=31068700; Sanger).
Omics: CRISPR phenotypic screen.
Omics: Deep exome analysis.
Omics: Deep quantitative proteome analysis.
Omics: DNA methylation analysis.
Omics: Protein expression by reverse-phase protein arrays.
Omics: SNP array analysis.
Omics: Transcriptome analysis by microarray.
Omics: Transcriptome analysis by RNAseq.
Misspelling: MUGC-3; Cosmic=1187288; PubMed=19132987.
Misspelling: NVGC3; Cosmic=801341.
Derived from site: Metastatic; Brachialis muscle; UBERON=UBERON_0001506.

PubMed=3325673; DOI=10.1007/BF02470755

Watanabe T., Nishikimi M., Akiyama S., Sakamoto J., Shiku H., Ichihashi H., Ozawa T., Kondo T., Takagi H.

A stomach oncofetal antigen recognized by monoclonal antibody GC302.

Jpn. J. Surg. 17:507-516(1987)

 

PubMed=3172586; DOI=10.1007/BF02471470

Akiyama S., Amo H., Watanabe T., Matsuyama M., Sakamoto J., Imaizumi M., Ichihashi H., Kondo T., Takagi H.

Characteristics of three human gastric cancer cell lines, NU-GC-2, NU-GC-3 and NU-GC-4.

Jpn. J. Surg. 18:438-446(1988)

 

PubMed=1778766; DOI=10.1111/j.1349-7006.1991.tb01816.x; PMCID=PMC5918361

Takeshima E., Hamaguchi M., Watanabe T., Akiyama S., Kataoka M., Ohnishi Y., Xiao H.-Y., Nagai Y., Takagi H.

Aberrant elevation of tyrosine-specific phosphorylation in human gastric cancer cells.

Jpn. J. Cancer Res. 82:1428-1435(1991)

 

PubMed=1370612; DOI=10.1016/S0006-291X(05)80133-0

Matozaki T., Sakamoto C., Matsuda K., Suzuki T., Konda Y., Nakano O., Wada K., Uchida T., Nishisaki H., Nagao M., Kasuga M.

Missense mutations and a deletion of the p53 gene in human gastric cancer.

Biochem. Biophys. Res. Commun. 182:215-223(1992)

 

PubMed=9290701; DOI=10.1002/(SICI)1098-2744(199708)19:4<243::AID-MC5>3.0.CO;2-D

Jia L.-Q., Osada M., Ishioka C., Gamo M., Ikawa S., Suzuki T., Shimodaira H., Niitani T., Kudo T., Akiyama M., Kimura N., Matsuo M., Mizusawa H., Tanaka N., Koyama H., Namba M., Kanamaru R., Kuroki T.

Screening the p53 status of human cell lines using a yeast functional assay.

Mol. Carcinog. 19:243-253(1997)

 

PubMed=15723654; DOI=10.1111/j.1349-7006.2005.00016.x; PMCID=PMC11160020

Takada H., Imoto I., Tsuda H., Sonoda I., Ichikura T., Mochizuki H., Okanoue T., Inazawa J.

Screening of DNA copy-number aberrations in gastric cancer cell lines by array-based comparative genomic hybridization.

Cancer Sci. 96:100-110(2005)

 

PubMed=15767549; DOI=10.1158/1535-7163.MCT-04-0234

Nakatsu N., Yoshida Y., Yamazaki K., Nakamura T., Dan S., Fukui Y., Yamori T.

Chemosensitivity profile of cancer cell lines and identification of genes determining chemosensitivity by an integrated bioinformatical approach using cDNA arrays.

Mol. Cancer Ther. 4:399-412(2005)

 

PubMed=19132987; DOI=10.1111/j.1600-0463.2008.01042.x

Li Y.-Q., Tanaka Y., Tada M., Hua R., Seto M., Asaoka Y., Ohta M., Kanai F., Yoshida H., Kawabe T., Sano T., Motojima T., Yokosuka O., Omata M.

Absence of the AKT1 pleckstrin homology domain mutation in Japanese gastrointestinal and liver cancer patients.

APMIS 116:931-933(2008)

 

PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113

Bignell G.R., Greenman C.D., Davies H.R., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B.-Y., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F.-T., Campbell P.J., Futreal P.A., Stratton M.R.

Signatures of mutation and selection in the cancer genome.

Nature 463:893-898(2010)

 

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662

Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P., Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J., Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C., Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J., Haber D.A.

A genome-wide screen for microdeletio