Marc-145细胞

Marc-145/Marc-145细胞系/Marc-145细胞株/Marc-145猴胚胎肾上皮细胞

Cell line name MARC-145

Synonyms Marc-145; MARC 145; Marc 145; MARC145; Marc145; Meat Animal Research Center-145

Accession CVCL_4540

Resource Identification Initiative To cite this cell line use: MARC-145 (RRID:CVCL_4540)

Comments Group: Non-human primate cell line.

Group: Patented cell line.

Problematic cell line: Misidentified. Parent cell line (MA-104) has been shown to be from African Green monkey instead of Rhesus macaque.

Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00621.

Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-12219.

Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-12230.

Virology: Highly susceptible to infection by porcine reproductive and respiratory syndrome virus (PRRSV).

Omics: Transcriptome analysis by microarray.

Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.

Species of origin Chlorocebus pygerythrus (Vervet monkey) (Cercopithecus pygerythrus) (NCBI Taxonomy: 60710)

Hierarchy Parent: CVCL_3845 (MA-104)

Children:

CVCL_1T05 (LN 14832) CVCL_B6C8 (MARC-145 PBD-1+EGFP clone 9/D6) CVCL_VG41 (MARC-145 pig CD163)

CVCL_HA70 (MARC-Nsp11)

Sex of cell Sex unspecified

Age at sampling Fetus

Category Spontaneously immortalized cell line

Publications

PubMed=8257302; DOI=10.1007/BF01313785

Kim H.S., Kwang J., Yoon I.J., Joo H.S., Frey M.L.

Enhanced replication of porcine reproductive and respiratory syndrome (PRRS) virus in a homogeneous subpopulation of MA-104 cell line.

Arch. Virol. 133:477-483(1993)

 

Patent=US5690940

Joo H.S.

Low pathogencity PRRS live virus vaccines and methods of preparation thereof.

Patent number US5690940, 25-Nov-1997

 

PubMed=17081295; DOI=10.1186/1743-422X-3-90; PMCID=PMC1635561

Cafruny W.A., Duman R.G., Wong G.H.W., Said S., Ward-Demo P., Rowland R.R.R., Nelson E.A.

Porcine reproductive and respiratory syndrome virus (PRRSV) infection spreads by cell-to-cell transfer in cultured MARC-145 cells, is dependent on an intact cytoskeleton, and is suppressed by drug-targeting of cell permissiveness to virus infection.

Virol. J. 3:90.1-90.17(2006)

 

PubMed=23148668; DOI=10.1186/1743-422X-9-267; PMCID=PMC3546013

Provost C., Jia J.-J., Music N., Levesque C., Lebel M.-E., del Castillo J.R.E., Jacques M., Gagnon C.A.

Identification of a new cell line permissive to porcine reproductive and respiratory syndrome virus infection and replication which is phenotypically distinct from MARC-145 cell line.

Virol. J. 9:267.1-267.14(2012)

 

PubMed=28046048; DOI=10.1371/journal.pone.0169391; PMCID=PMC5207746

Dotti S., Lombardo T., Villa R., Cacciamali A., Zanotti C., Andreani N.A., Cinotti S., Ferrari M.

Transformation and tumorigenicity testing of simian cell lines and evaluation of poliovirus replication.

PLoS ONE 12:E0169391-E0169391(2017)

 

PubMed=29682543; DOI=10.1155/2018/4315861; PMCID=PMC5841097

Wu X.-J., Qi J., Cong X.-Y., Chen L., Hu Y., Yoo D.-W., Wang G.-S., Tian F.-L., Li F., Sun W.-B., Chen Z., Guo L.-H., Wu J.-Q., Li J., Wang J.-B., Zhao X.-M., Du Y.-J.

Establishment and characterization of a high and stable porcine CD163-expressing MARC-145 cell line.

BioMed Res. Int. 2018:4315861.1-4315861.9(2018)

 

PubMed=33268540; DOI=10.1128/jcm.01757-20; PMCID=PMC8106717

Yim-im W., Huang H.-Y., Park J., Wang C., Calzada-Nova G., Gauger P., Harmon K., Main R., Zhang J.-Q.

Comparison of ZMAC and MARC-145 cell lines for improving porcine reproductive and respiratory syndrome virus isolation from clinical samples.

J. Clin. Microbiol. 59:e01757.20.1-e01757.20.15(2021)

 

PubMed=34205087; DOI=10.3390/vaccines9060594; PMCID=PMC8229515

Xie J.-X., Vereecke N., Theuns S., Oh D.-Y., Vanderheijden N., Trus I., Sauer J., Vyt P., Bonckaert C., Lalonde C., Provost C., Gagnon C.A., Nauwynck H.J.

Comparison of primary virus isolation in pulmonary alveolar macrophages and four different continuous cell lines for type 1 and type 2 porcine reproductive and respiratory syndrome virus.

Vaccines (Basel) 9:594.1-594.13(2021)

 

PubMed=34737324; DOI=10.1038/s41598-021-00779-5; PMCID=PMC8569163

Lung O., Candlish R.C., Nebroski M., Kruckiewicz P., Buchanan C., Moniwa M.

High-throughput sequencing for species authentication and contamination detection of 63 cell lines.

Sci. Rep. 11:21657-21657(2021)