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- 详细信息
- 技术资料
- 标记物:
Unconjugated
- 适应物种:
Human;Mouse
- 供应商:
武汉恩玑生命科技有限公司
- 宿主:
Rabbit
- 应用范围:
WB;IP
- 规格:
50uL/100uL
| 规格: | 50uL | 产品价格: | ¥1350.0 |
|---|---|---|---|
| 规格: | 100uL | 产品价格: | ¥2250.0 |
产品概述
产品性能
免疫原
产品应用
研究背景
Multifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. Accomplishes its multiple functions by interacting with distinct downstream effectors. Acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles . Required both to stabilize the assembly of the exocyst complex and to localize functional exocyst complexes to the leading edge of migrating cells . Required for suppression of apoptosis (PubMed:17875936). In late stages of cytokinesis, upon completion of the bridge formation between dividing cells, mediates exocyst recruitment to the midbody to drive abscission (PubMed:18756269).
研究领域
Signal Transduction
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