- ￥1350 - 2250
- EnkiLife
- AMRe01771
- 2025年07月14日
- WB;IF/ICC;IP
- Rabbit
- Human
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- 详细信息
- 技术资料
- 标记物：
Unconjugated
- 适应物种：
Human
- 供应商：
武汉恩玑生命科技有限公司
- 宿主：
Rabbit
- 应用范围：
WB;IF/ICC;IP
- 规格：
50uL/100uL
| 规格： | 50uL | 产品价格： | ￥1350.0 |
|---|---|---|---|
| 规格： | 100uL | 产品价格： | ￥2250.0 |
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免疫原
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研究背景
This gene is a proto-oncogene that encodes a RING finger E3 ubiquitin ligase. The encoded protein is one of the enzymes required for targeting substrates for degradation by the proteasome. This protein mediates the transfer of ubiquitin from ubiquitin conjugating enzymes (E2) to specific substrates. This protein also contains an N-terminal phosphotyrosine binding domain that allows it to interact with numerous tyrosine-phosphorylated substrates and target them for proteasome degradation. As such it functions as a negative regulator of many signal transduction pathways. This gene has been found to be mutated or translocated in many cancers including acute myeloid leukaemia. Mutations in this gene are also the cause of Noonan syndrome-like disorder
研究领域
Cell Biology
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