Phospho-COT (Thr290) Rabbit Polyclonal Antibody

Phospho-COT (Thr290) Rabbit Po

lyclonal Antibody
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  • ¥1350 - 2250
  • EnkiLife
  • APRab00909
  • 2025年12月13日
  • WB;IHC;IF/ICC;ELISA
  • Rabbit
  • Human;Mouse;Rat
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  • 企业认证

    • 详细信息
    • 技术资料
    • 标记物

      Unconjugated

    • 适应物种

      Human;Mouse;Rat

    • 供应商

      武汉恩玑生命科技有限公司

    • 宿主

      Rabbit

    • 应用范围

      WB;IHC;IF/ICC;ELISA

    • 规格

      50uL/100uL

    规格:50uL产品价格:¥1350.0
    规格:100uL产品价格:¥2250.0

    产品概述

    产品名称(Product Name)

    Phospho-COT (Thr290) Rabbit Polyclonal Antibody

    描述(Description)

    Primary antibody

    宿主(Host)

    Rabbit

    应用(Application)

    WB,IHC-P,ICC/IF,ELISA

    种属反应性(Reactivity)

    Human,Mouse,Rat

     

    产品性能

    偶联物(Conjugation)

    Unconjugated

    修饰(Modification)

    Phosphorylated

    同种型(Isotype)

    IgG

    克隆(Clonality)

    Polyclonal Antibody

    形式(Form)

    Liquid

    存放说明(Storage)

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

    储存溶液(Buffer)

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

    纯化方式(Purification)

    Affinity Chromatography

     

    免疫原

    基因名(Gene Name)

    MAP3K8

    别名(Alternative Names)

    Mitogen-activated protein kinase kinase kinase 8; Cancer Osaka thyroid oncogene; Proto-oncogene c-Cot; Serine/threonine-protein kinase cot; Tumor progression locus 2

    基因ID(Gene ID)

    1326

    蛋白ID(SwissProt ID)

    P41279

     

    产品应用

    稀释比(Dilution Ratio)

    WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 ELISA: 1/10000

    蛋白分子量(Molecular Weight)

    Calculated MW: 53 kDa; Observed MW: 60 kDa

     

    研究背景

    mitogen-activated protein kinase kinase kinase 8(MAP3K8) Homo sapiens This gene is an oncogene that encodes a member of the serine/threonine protein kinase family. The encoded protein localizes to the cytoplasm and can activate both the MAP kinase and JNK kinase pathways. This protein was shown to activate IkappaB kinases, and thus induce the nuclear production of NF-kappaB. This protein was also found to promote the production of TNF-alpha and IL-2 during T lymphocyte activation. This gene may also utilize a downstream in-frame translation start codon, and thus produce an isoform containing a shorter N-terminus. The shorter isoform has been shown to display weaker transforming activity. Alternate splicing results in multiple transcript variants that encode the same protein.

     

    研究领域

    Signal Transduction

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