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- 详细信息
- 文献和实验
- 技术资料
- 英文名:
IL-18 BPd/Interleukin-18 binding protein isoform d
- 供应商:
武汉恩玑生命科技有限公司
- 规格:
10ug/50ug/500ug
| 规格: | 10ug | 产品价格: | ¥470.0 |
|---|---|---|---|
| 规格: | 50ug | 产品价格: | ¥1100.0 |
| 规格: | 500ug | 产品价格: | ¥8000.0 |
| 产品名称 |
Recombinant Mouse IL-18BPd (C-Fc) |
| 英文名称 |
IL-18 BPd/Interleukin-18 binding protein isoform d |
| 纯度 |
Greater than 95% as determined by reducing SDS-PAGE |
| 内毒素 |
<1 EU/µg as determined by LAL test. |
| 蛋白构建 |
Recombinant Mouse Interleukin-18 Binding Protein Isoform d is produced by our Mammalian expression system and the target gene encoding Thr29-Ala193 is expressed with a human IgG1 Fc tag at the C-terminus. |
| Accession |
Q9Z0M9 |
| 表达宿主 |
Human Cells |
| 种属 |
Mouse |
| 预测分子量 |
45.1 KDa |
| 制剂 |
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
| 运输方式 |
The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below. |
| 稳定性&储存 |
Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.Reconstituted protein solution can be stored at 2-8°C for 2-7 days.Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 |
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 分子别名 |
| Interleukin 18 Binding Protein Isoform d; IL-18 BPd;Interleukin-18-binding protein;Interferon gamma-inducing factor-binding protein;Igifbp |
| 背景介绍 |
| Interleukin 18 binding protein (IL-18BP) is a physiological inhibitor that acts through binding to the receptor-binding site of IL-18. IL-18 stimulates INF-γ, which then stimulates 18BP production via NF-κB. The interaction between IL-18 and IL-18BP has a significant role in the inflammation process. IL-18 BPs have four isoforms, a, b, c and d, which are spliced by different ways. The IL-18 BP isoforms a and c each contain one immunoglobulin (Ig)-like C2-type domain which is essential to the binding and neutralizing properties of the binding proteins. The IL-18 BP isoforms b and d lack a complete Ig domain. The expression of IL-18 and the IL-18BP are indentified in immune tissues such as the spleen, but also in nonimmune cells including keratinocytes. |
注意事项
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文献和实验depends on product and its function. N-terminal sequencing revealed that the purified rBoNTC(Hc )-N is missing the first eight amino acids of the N-terminus of the protein, whereas the purified rBoNTC(Hc )-C protein is intact. After a mouse bioassay test
Expression of Recombinant Cytochromes c in E. coli
for proper folding and stability. However, significant advances in expression of recombinant cytochromes c have been made during the last decade. It has been shown that a single gene cluster, ccmA–H , is responsible for cytochrome c maturation in Escherichia
上海西唐生物科技有限公司 021-55229872, 65333639 www.westang.com 大鼠白介素 -18(IL-18)ELISA 试剂盒 ( 用于血清、血浆、细胞培养上清液和其它生物体液内 ) 原理 本实验采用双抗体夹心 ABC-ELISA 法。用抗大鼠 IL-18 单抗包被于酶标板上,标准品和样品中的 IL-18 与单抗结合,加入生物素化的抗大鼠 IL-18 ,形成免疫复合物连接
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