- ￥760 - 10980
- EnkiLife
- PEH0694
- 2025年11月13日
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- 详细信息
- 技术资料
- 英文名：
GABA(A) receptor-associated protein/GABARAP
- 供应商：
武汉恩玑生命科技有限公司
- 规格：
10ug/50ug/500ug
| 规格： | 10ug | 产品价格： | ￥760.0 |
|---|---|---|---|
| 规格： | 50ug | 产品价格： | ￥2280.0 |
| 规格： | 500ug | 产品价格： | ￥10980.0 |
| 产品名称 |
Recombinant Human GABARAP (N-6His, C-Fc) |
| 英文名称 |
GABA(A) receptor-associated protein/GABARAP |
| 纯度 |
Greater than 95% as determined by reducing SDS-PAGE |
| 内毒素 |
<1 EU/µg as determined by LAL test. |
| 蛋白构建 |
Recombinant Human GABA(A) Receptor-Associated Protein is produced by our E.coli expression system and the target gene encoding Met1-Leu117 is expressed with a 6His tag at the N-terminus, human IgG1 Fc tag at the C-terminus. |
| Accession |
Q6IAW1 |
| 表达宿主 |
E.coli |
| 种属 |
Human |
| 预测分子量 |
43.2 KDa |
| 制剂 |
Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 20% Glycerol, pH 7.0. |
| 运输方式 |
The product is shipped on dry ice/polar packs.Upon receipt, store it immediately at the temperature listed below. |
| 稳定性&储存 |
Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 复溶 |
| 分子别名 |
| GABA(A) Receptor-Associated Protein; GABARAP Protein; HCG1987397 Isoform CRA_b; GABARAP |
| 背景介绍 |
| Gamma-Aminobutyric Acid Receptor-Associated Protein (GABARAP) is a ligand-gated chloride channel protein that mediates inhibitory neurotransmission and belongs to the MAP1 LC3 family. GABARAP is highly positively charged in its N-terminus and shares sequence similarity with light chain-3 of microtubule-associated proteins 1A and 1B. GABARAP clusters neurotransmitter receptors by mediating interaction with the cytoskeleton. Autophagy is the process by which cells recycle cytoplasm and dispose of excess or defective organelles. This process is suggested to be involved development, differentiation, growth regulation and tissue remodeling in multicellular organisms. An important inhibitory neurotransmitter, GABA, acts on GABA receptors that are ubiquitously expressed in the CNS. GABARAP has been shown to play a important role in intracellular transport of GABA(A) receptors and its interaction with the cytoskeleton. |
注意事项
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