Recombinant Human CD19 (C-Fc)

Recombinant Human CD19 (C-Fc)

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  • ¥760 - 10980
  • EnkiLife
  • PCH0305
  • 2025年11月10日
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    • 详细信息
    • 技术资料
    • 英文名

      CD19/CD19 Molecule

    • 供应商

      武汉恩玑生命科技有限公司

    • 规格

      10ug/50ug/500ug

    规格:10ug产品价格:¥760.0
    规格:50ug产品价格:¥2280.0
    规格:500ug产品价格:¥10980.0
    产品名称

    Recombinant Human CD19 (C-Fc)

    英文名称

    CD19/CD19 Molecule  

    纯度

    Greater than 95% as determined by reducing SDS-PAGE

    内毒素

    <1 EU/µg as determined by LAL test.

    蛋白构建

    Recombinant Human CD19 is produced by our Mammalian expression system and the target gene encoding Pro20-Lys291 is expressed with a human IgG1 Fc tag at the C-terminus.

    Accession

    P15391

    表达宿主

    CHO Stable Cells

    种属

    Human

    预测分子量

    57.3 KDa

    制剂

    Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

    运输方式

    The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.

    稳定性&储存

    Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

    复溶

    Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

     

    分子别名
    B-Lymphocyte Antigen CD19; B-Lymphocyte Surface Antigen B4; Differentiation Antigen CD19; T-Cell Surface Antigen Leu-12; CD19

     

    背景介绍
    CD19 is a single-pass type I membrane protein containing 2 Ig-like C2-type (immunoglobulin-like) domains. CD19 is expressed on follicular dendritic cells and B cells. In fact, it is present on B cells from earliest recognizable B-lineage cells during development to B-cell blasts but is lost on maturation to plasma cells. CD19 primarily acts as a B cell co-receptor in conjunction with CD21 and CD81. Upon activation, the cytoplasmic tail of CD19 becomes phosphorylated, which leads to binding by Src-family kinases and recruitment of PI-3 kinase. CD19 Assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation.

     

    注意事项

    本司产品仅用于科研,不用于临床诊断和治疗

     

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