Recombinant Human BAI3 (C-6His)

Recombinant Human BAI3 (C-6His

)
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  • ¥760 - 10980
  • EnkiLife
  • PHH0168
  • 2025年11月10日
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  • 企业认证

    • 详细信息
    • 技术资料
    • 英文名

      Brain-specific angiogenesis inhibitor 3/BAI3

    • 供应商

      武汉恩玑生命科技有限公司

    • 规格

      10ug/50ug/500ug

    规格:10ug产品价格:¥760.0
    规格:50ug产品价格:¥2280.0
    规格:500ug产品价格:¥10980.0
    产品名称

    Recombinant Human BAI3 (C-6His)

    英文名称

    Brain-specific angiogenesis inhibitor 3/BAI3  

    纯度

    Greater than 95% as determined by reducing SDS-PAGE

    内毒素

    <1 EU/µg as determined by LAL test.

    蛋白构建

    Recombinant Human Brain-Specific Angiogenesis Inhibitor 3 is produced by our Mammalian expression system and the target gene encoding Ala25-Thr880 is expressed with a 6His tag at the C-terminus.

    Accession

    O60242

    表达宿主

    Human Cells

    种属

    Human

    预测分子量

    97.51 KDa

    制剂

    Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 5% Thehalose, pH 7.2.

    运输方式

    The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.

    稳定性&储存

    Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

    复溶

    Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

     

    分子别名
    Brain-Specific Angiogenesis Inhibitor 3; BAI3; KIAA0550

     

    背景介绍
    Human Brain-Specific Angiogenesis Inhibitor 3 (BAI3) is a 177 kDa seven-span transmembrane (TM) protein, which is thought to be a member of the secretin receptor family. It is synthesized by neurons of the CNS and likely is a negative regulator of angiogenesis. BAI3 is 1498 amino acids in size. It contains three distinct regions: an N-terminal extracellular domain (ECD) (aa25-883), a 7-TM segment, and a C-terminal cytoplasmic region. The ECD contains four antiangiogenic TSP type 1 repeat (aa296-508), and one GSP domain (aa 816-867) that is likely used to cleave the ECD from the membrane-bound receptor. There is one altermate splice form that shows a deletion of aa 643-665. Over aa 25-880, human BAI3 shares 98% aa identity with mouse BAI3. BAI3 has been reported primarily in the brain, but is also localized to lung, testis, and pancreas. It might be involved in angiogenesis inhibition and suppression of glioblastoma.

     

    注意事项

    本司产品仅用于科研,不用于临床诊断和治疗

     

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