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- 详细信息
- 技术资料
- 英文名:
IL-1RI/Interleukin-1 receptor type 1/IL-1R1
- 供应商:
武汉恩玑生命科技有限公司
- 规格:
10ug/50ug/500ug
| 规格: | 10ug | 产品价格: | ¥360.0 |
|---|---|---|---|
| 规格: | 50ug | 产品价格: | ¥1080.0 |
| 规格: | 500ug | 产品价格: | ¥4400.0 |
| 产品名称 |
Recombinant Mouse IL-1R1 (C-Fc) |
| 英文名称 |
IL-1RI/Interleukin-1 receptor type 1/IL-1R1 |
| 纯度 |
Greater than 95% as determined by reducing SDS-PAGE |
| 内毒素 |
<1 EU/µg as determined by LAL test. |
| 蛋白构建 |
Recombinant Mouse Interleukin-1 Receptor Type 1 is produced by our Mammalian expression system and the target gene encoding Leu20-Lys338 is expressed with a human IgG1 Fc tag at the C-terminus. |
| Accession |
P13504 |
| 表达宿主 |
Human Cells |
| 种属 |
Mouse |
| 预测分子量 |
64 KDa |
| 制剂 |
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
| 运输方式 |
The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below. |
| 稳定性&储存 |
Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 复溶 |
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 分子别名 |
| Interleukin-1 receptor type 1; IL-1R-1; IL-1RT-1; IL-1RT1; CD121 antigen-like family member A; Interleukin-1 receptor alpha; IL-1R-alpha; p80; CD121a; mIL-1R1 |
| 背景介绍 |
| Mouse Interleukin-1 receptor type 1/IL-1 RI is a cytokine receptor that belongs to the interleukin-1 receptor family. This protein is a receptor for interleukin 1 alpha (IL1A), interleukin 1 beta (IL1B), and interleukin 1 receptor antagonist (IL1RA). It is an important mediator involved in many cytokine induced immune and inflammatory responses. An IL1 receptor accessory protein that can heterodimerize with the Type I receptor in the presence of IL1α or IL1βbut not IL1ra, was identified. This Type I receptor complex appears to mediate all the known IL1 biological responses. The receptor Type II has a short cytoplasmic domain and does not transduce IL1 signals. In addition to the membranebound form of IL1 RII, a naturallyoccurring soluble form of IL1 RII has been described. It has been suggested that the Type II receptor, either as the membranebound or as the soluble form, serves as a decoy for IL1 and inhibits IL1 action by blocking the binding of IL1 to the signaling Type I receptor complex. |
注意事项
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