Recombinant Mouse IL-1R1 (C-Fc)

Recombinant Mouse IL-1R1 (C-Fc

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  • ¥360 - 4400
  • EnkiLife
  • PHM0975
  • 2025年07月12日
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    • 详细信息
    • 技术资料
    • 英文名

      IL-1RI/Interleukin-1 receptor type 1/IL-1R1

    • 供应商

      武汉恩玑生命科技有限公司

    • 规格

      10ug/50ug/500ug

    规格:10ug产品价格:¥360.0
    规格:50ug产品价格:¥1080.0
    规格:500ug产品价格:¥4400.0
    产品名称

    Recombinant Mouse IL-1R1 (C-Fc)

    英文名称

    IL-1RI/Interleukin-1 receptor type 1/IL-1R1  

    纯度

    Greater than 95% as determined by reducing SDS-PAGE

    内毒素

    <1 EU/µg as determined by LAL test.

    蛋白构建

    Recombinant Mouse Interleukin-1 Receptor Type 1 is produced by our Mammalian expression system and the target gene encoding Leu20-Lys338 is expressed with a human IgG1 Fc tag at the C-terminus.

    Accession

    P13504

    表达宿主

    Human Cells

    种属

    Mouse

    预测分子量

    64 KDa

    制剂

    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

    运输方式

    The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.

    稳定性&储存

    Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

    复溶

    Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

     

    分子别名
    Interleukin-1 receptor type 1; IL-1R-1; IL-1RT-1; IL-1RT1; CD121 antigen-like family member A; Interleukin-1 receptor alpha; IL-1R-alpha; p80; CD121a; mIL-1R1

     

    背景介绍
    Mouse Interleukin-1 receptor type 1/IL-1 RI is a cytokine receptor that belongs to the interleukin-1 receptor family. This protein is a receptor for interleukin 1 alpha (IL1A), interleukin 1 beta (IL1B), and interleukin 1 receptor antagonist (IL1RA). It is an important mediator involved in many cytokine induced immune and inflammatory responses. An IL1 receptor accessory protein that can heterodimerize with the Type I receptor in the presence of IL1α or IL1βbut not IL1ra, was identified. This Type I receptor complex appears to mediate all the known IL1 biological responses. The receptor Type II has a short cytoplasmic domain and does not transduce IL1 signals. In addition to the membranebound form of IL1 RII, a naturallyoccurring soluble form of IL1 RII has been described. It has been suggested that the Type II receptor, either as the membranebound or as the soluble form, serves as a decoy for IL1 and inhibits IL1 action by blocking the binding of IL1 to the signaling Type I receptor complex.

     

    注意事项

    本司产品仅用于科研,不用于临床诊断和治疗

     

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