Recombinant Human ITM2B (C-6His)

Recombinant Human ITM2B (C-6Hi

s)
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  • ¥1080 - 11000
  • EnkiLife
  • PHH1023
  • 2025年10月23日
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    • 详细信息
    • 技术资料
    • 英文名

      ITM2B/imBRI2/BRI

    • 供应商

      武汉恩玑生命科技有限公司

    • 规格

      10ug/50ug/500ug

    规格:10ug产品价格:¥1080.0
    规格:50ug产品价格:¥3180.0
    规格:500ug产品价格:¥11000.0
    产品名称

    Recombinant Human ITM2B (C-6His)

    英文名称

    ITM2B/imBRI2/BRI  

    纯度

    Greater than 95% as determined by reducing SDS-PAGE

    内毒素

    <1 EU/µg as determined by LAL test.

    蛋白构建

    Recombinant Human Integral Membrane Protein 2B is produced by our Mammalian expression system and the target gene encoding Tyr76-Ser266 is expressed with a 6His tag at the C-terminus.

    Accession

    Q9Y287

    表达宿主

    Human Cells

    种属

    Human

    预测分子量

    23.3 KDa

    制剂

    Supplied as a 0.2 μm filtered solution of 20mM Acetate, 10% Trehalose, 25mM NaCl, 10% Glycerol, 0.05% Tween 80, pH 4.5.

    运输方式

    The product is shipped on dry ice/polar packs.Upon receipt, store it immediately at the temperature listed below.

    稳定性&储存

    Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening.Please minimize freeze-thaw cycles.

    复溶

     

    分子别名
    Integral Membrane Protein 2B; Immature BRI2; imBRI2; Protein E25B; Transmembrane Protein BRI; Bri; ITM2B; BRI; BRI2

     

    背景介绍
    Integral Membrane Protein 2B (ITM2B) is expressed in the Golgi and on the cell surface. ITM2B forms homodimer through disulfide-linked interaction with SPPL2A, SPPL2B and APP. ITM2B is expressed in brain and the other tissues. Defects in ITM2B cause cerebral amyloid angiopathy ITM2B-related type 1(CAA-ITM2B1) and amyloid angiopathy ITM2B-related type 2(CAA-ITM2B2). CAA-ITM2B1 is characterized by amyloid deposition in the walls of cerebral blood vessels and neurodegeneration in the central nervous system. CAA-ITM2B2 characterized by amyloid deposition in the walls of the blood vessels of the cerebrum, choroid plexus, cerebellum, spinal cord and retina.

     

    注意事项

    本司产品仅用于科研,不用于临床诊断和治疗

     

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    Recombinant Human ITM2B (C-6His)
    ¥1080 - 11000