Recombinant Human BTN3A1 (C-Fc)

Recombinant Human BTN3A1 (C-Fc

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  • ¥540 - 9000
  • EnkiLife
  • PHH0177
  • 2025年11月15日
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    • 详细信息
    • 技术资料
    • 英文名

      BTN3A1/Butyrophilin Subfamily 3 Member A1/CD277

    • 供应商

      武汉恩玑生命科技有限公司

    • 规格

      10ug/50ug/500ug

    规格:10ug产品价格:¥540.0
    规格:50ug产品价格:¥1300.0
    规格:500ug产品价格:¥9000.0
    产品名称

    Recombinant Human BTN3A1 (C-Fc)

    英文名称

    BTN3A1/Butyrophilin Subfamily 3 Member A1/CD277   

    纯度

    Greater than 95% as determined by reducing SDS-PAGE

    内毒素

    <1 EU/µg as determined by LAL test.

    蛋白构建

    Recombinant Human Butyrophilin Subfamily 3 Member A1 is produced by our Mammalian expression system and the target gene encoding Gln30-Gly254 is expressed with a human IgG1 Fc tag at the C-terminus.

    Accession

    O00481

    表达宿主

    Human Cells

    种属

    Human

    预测分子量

    50.8 KDa

    制剂

    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

    运输方式

    The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.

    稳定性&储存

    Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

    复溶

    Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

     

    分子别名
    Butyrophilin subfamily 3 member A1; CD277; BTN3A1; BTF5

     

    背景介绍
    Butyrophilin Subfamily 3 Member A1 (BTN3A1/CD277) is a type I transmembrane glycoprotein member of the Ig superfamily. It is expressed on a wide variety of immune cells. Similar to BTN3A2 and BTN3A3, BTN3A1 is composed of an extracellular N-terminal IgV and a membraneproximal IgC domain followed by a transmembrane domain and a cytoplasmic tail. These Ig domains are also found in B7 family costimulatory molecules, suggesting structural and functional similarities between the two protein families. BTN3A1 acts as a critical protein for the activation of Vγ9Vδ2 T cells following detection of distressed cells. The anti-tumor responses of Vγ9Vδ2 T cells may be enhanced with agonistic anti-BTNA3 antibodies.

     

    注意事项

    本司产品仅用于科研,不用于临床诊断和治疗

     

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