Recombinant Human PRKAR1A (C-6His)

Recombinant Human PRKAR1A (C-6

His)
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  • ¥360 - 4800
  • EnkiLife
  • PHH1367
  • 2025年10月21日
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    • 详细信息
    • 技术资料
    • 英文名

      PRKAR1A/TSE1

    • 供应商

      武汉恩玑生命科技有限公司

    • 规格

      10ug/50ug/500ug

    规格:10ug产品价格:¥360.0
    规格:50ug产品价格:¥760.0
    规格:500ug产品价格:¥4800.0
    产品名称

    Recombinant Human PRKAR1A (C-6His)

    英文名称

    PRKAR1A/TSE1  

    纯度

    Greater than 95% as determined by reducing SDS-PAGE

    内毒素

    <1 EU/µg as determined by LAL test.

    蛋白构建

    Recombinant Human cAMP-dependent Protein Kinase Regulatory Type I-alpha is produced by our Mammalian expression system and the target gene encoding Glu2-Val381 is expressed with a 6His tag at the C-terminus.

    Accession

    P10644

    表达宿主

    Human Cells

    种属

    Human

    预测分子量

    44 KDa

    制剂

    Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

    运输方式

    The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.

    稳定性&储存

    Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

    复溶

    Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

     

    分子别名
    Tissue-specific extinguisher 1;TSE1

     

    背景介绍
    cAMP-dependent protein kinase type I-alpha regulatory subunit is an enzyme that in humans is encoded by the PRKAR1A gene. cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase A (PKA), which transduces the signal through phosphorylationof different target proteins. Four different regulatory subunits and three catalytic subunits of PKA have been identified in humans. The protein encoded by this gene is one of the regulatory subunits. This protein was found to be a tissue-specific extinguisher that down-regulates the expression of seven liver genes in hepatoma x fibroblast hybrids.

     

    注意事项

    本司产品仅用于科研,不用于临床诊断和治疗

     

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