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- 2025年09月26日
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- 详细信息
- 文献和实验
- 技术资料
- 英文名：
Serpin B3/SERPINB3/SCCA1
- 供应商：
武汉恩玑生命科技有限公司
- 规格：
10ug/50ug/500ug
| 规格： | 10ug | 产品价格： | ￥1080.0 |
|---|---|---|---|
| 规格： | 50ug | 产品价格： | ￥3180.0 |
| 规格： | 500ug | 产品价格： | ￥12200.0 |
| 产品名称 |
Recombinant Human Serpin B3 (N-6His) |
| 英文名称 |
Serpin B3/SERPINB3/SCCA1 |
| 纯度 |
Greater than 95% as determined by reducing SDS-PAGE |
| 内毒素 |
<1 EU/µg as determined by LAL test. |
| 蛋白构建 |
Recombinant Human Serine Protease Inhibitor-clade B3 is produced by our E.coli expression system and the target gene encoding Met1-Pro390 is expressed with a 6His tag at the N-terminus. |
| Accession |
P29508 |
| 表达宿主 |
E.coli |
| 种属 |
Human |
| 预测分子量 |
46 KDa |
| 制剂 |
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
| 运输方式 |
The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below. |
| 稳定性&储存 |
Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 复溶 |
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 分子别名 |
| Serpin B3; Protein T4-A; Squamous cell carcinoma antigen 1; SCCA-1;serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 3; serpin peptidase inhibitor, clade B (ovalbumin), member 3; Squamous cell carcinoma antigen 1; T4-A;SCCA1 |
| 背景介绍 |
| Serpin B3, also known as squamous cell carcinoma antigen-1 (SCCA-1), is a member of the serpin superfamily of serine protease inhibitors. Serpin B3 belongs to the subgroup ovalbumin-related serpins which are involved in the regulation of apoptosis, inflammation, angiogenesis and embryogenesis. It may act as a papain-like cysteine protease inhibitor to modulate the host immune response against tumor cells. It also functions as an inhibitor of UV-induced apoptosis via suppression of the activity of c-Jun NH(2)-terminal kinase (JNK1). |
注意事项
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文献和实验Expression of Recombinant Proteins with Uniform N-Termini
that recombinant proteins produced in this expression system contain homogeneous, unprocessed N-termini.
High Throughput Production of Recombinant Human Proteins for Crystallography
This chapter presents in detail the process used in high throughput bacterial production of recombinant human proteins for crystal structure determination. The core principles are: (1 ) Generating at least 10 truncated constructs
and centrally located DNA-binding domain (DBD), and a poorly characterized N-terminal domain that is required for maximal transcriptional activity (1 ,2 ) Human PR is expressed as two proteins from a single gene by alternate use of two promoters: PR
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