HTRA2抗体;HTRA2 Polyclonal Antib

Description This gene encodes a serine protease. The protein has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen-activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat-containing 4. Nuclear localization of this protein has also been observed. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016] References 1.Br J Cancer. 2015 Feb 17;112(4):739-44. 2.Pathol Res Pract. 2014 Dec;210(12):939-43. Specification Aliases:OMI; MGCA8; PARK13; PRSS25 Entrez GeneID:27429 Swissprot:O43464 clone:6H7A8 WB Predicted band size:48.8kDa Host/Isotype:Mouse IgG1 Antibody Type:Primary antibody Storage:Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. Species Reactivity:Human,Mouse,Rat Immunogen:Purified recombinant fragment of human HTRA2 (AA: 278-458) expressed in E. Coli. Formulation:Purified antibody in PBS with 0.05% sodium azide Application WB:1/500 - 1/2000 IHC:1/200 - 1/1000 FCM:1/200 - 1/400 ELISA:1/10000