LRP1抗体;LRP1 Polyclonal Antibod

Description The protein encoded by this gene is an endocytic receptor involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells. In addition, the encoded protein is necessary for the A2M-mediated clearance of secreted amyloid precursor protein and beta-amyloid, the main component of amyloid plaques found in Alzheimer patients. Expression of this gene decreases with age and has been found to be lower than controls in brain tissue from Alzheimer patients. References 1.J Biol Chem. 2014 Feb 14;289(7):4135-44. 2.Aging (Albany NY). 2013 Nov;5(11):835-49. Specification Aliases:APR; LRP; A2MR; CD91; APOER; LRP1A; TGFBR5; IGFBP3R Entrez GeneID:4035 Swissprot:Q07954 clone:3F12E2 WB Predicted band size:50.5kDa Host/Isotype:Mouse IgG1 Antibody Type:Primary antibody Storage:Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. Species Reactivity:Human Immunogen:Purified recombinant fragment of human LRP1 (AA: 20-155) expressed in E. Coli. Formulation:Purified antibody in PBS with 0.05% sodium azide Application IHC:1/200 - 1/1000 ICC:1/200 - 1/1000 FCM:1/200 - 1/400 ELISA:1/10000