CD63抗体;CD63 Polyclonal Antibod

Description The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms. References 1.J Invest Dermatol. 2014 Dec;134(12):2947-2956. 2.Eur J Immunol. 2011 Sep;41(9):2556-61. Specification Aliases:MLA1; ME491; LAMP-3; OMA81H; TSPAN30 Entrez GeneID:967 Swissprot:P08962 clone:1E8D4 WB Predicted band size:25.6kDa Host/Isotype:Mouse IgG1 Antibody Type:Primary antibody Storage:Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. Species Reactivity:Human Immunogen:Purified recombinant fragment of human CD63 (AA: extra 103-203) expressed in E. Coli. Formulation:Purified antibody in PBS with 0.05% sodium azide Application IHC:1/200 - 1/1000 FCM:1/200 - 1/400 ELISA:1/10000