SOX2抗体;SOX2 Polyclonal Antibod

Description SOX2: SRY (sex determining region Y)-box 2. Entrez Protein NP_003097. It is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). References 1. Exp Neurol. 2007 Apr;204(2):828-31. 2. Nature. 2008 Jan 10;451(7175):141-6. Specification Aliases:ANOP3; MCOPS3; MGC2413 Entrez GeneID:6657 Swissprot:P48431 clone:10F10C9 WB Predicted band size:34.3kDa Host/Isotype:Mouse IgG1 Antibody Type:Primary antibody Storage:Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. Species Reactivity:Human Immunogen:Purified recombinant fragment of SOX2 (aa1-170) expressed in E. Coli. Formulation:Ascitic fluid containing 0.03% sodium azide. Application ELISA:1/10000