PPY抗体;PPY Polyclonal Antibody

Description This gene belongs to the NPY family and it encodes a protein that is synthesized as a 95 aa polypeptide precursor in the pancreatic islets of Langerhans. It is cleaved into two peptide products; the active hormone of 36 aa and an icosapeptide of unknown function. The hormone acts as a regulator of pancreatic and gastrointestinal functions and may be important in the regulation of food intake. Plasma level of this hormone has been shown to be reduced in conditions associated with increased food intake and elevated in anorexia nervosa. In addition, infusion of this hormone in obese rodents has shown to decrease weight gain. References 1.Am J Clin Nutr. 2011 Oct;94(4):967-72. 2.Pharm Res. 2012 Jun;29(6):1698-711. Specification Aliases:PNP Entrez GeneID:5539 Swissprot:P01298 clone:2G5D12 WB Predicted band size:10.4kDa Host/Isotype:Mouse IgG1 Antibody Type:Primary antibody Storage:Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. Species Reactivity:Human Immunogen:Purified recombinant fragment of human PPY (AA: 1-95) expressed in E. Coli. Formulation:Purified antibody in PBS with 0.05% sodium azide Application FCM:1/200 - 1/400 ELISA:1/10000