MECOM抗体;MECOM Polyclonal Antib

Description The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene. Specification Aliases:EVI1; MDS1; KMT8E; PRDM3; RUSAT2; MDS1-EVI1; AML1-EVI-1 Swissprot:Q03112 WB Predicted band size:118 kDa Host/Isotype:Rabbit IgG Antibody Type:Primary antibody Storage:Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. Species Reactivity:Human, Mouse Immunogen:Synthetic peptide of human MECOM Formulation:pH7.4 PBS, 0.05% NaN3, 40% Glycerol Application WB:1/200-1/1000 IHC:1/30-1/150 ELISA:1/5000-1/10000