PDK1抗体;PDK1 Polyclonal Antibod

Description Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. (provided by RefSeq). Tissue specificity: Expressed predominantly in the heart. References 1. Nat Cell Biol. 2008 Feb;10(2):127-37. 2. Blood. 2008 Apr 1;111(7):3723-34. 3. J Biol Chem. 2007 Apr 20;282(16):12272-89. Specification Aliases:PDK1 Entrez GeneID:5163 Swissprot:Q15118 clone:4A11 WB Predicted band size:44kDa Host/Isotype:Mouse IgG1 Antibody Type:Primary antibody Storage:Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. Species Reactivity:Human,Rat,Monkey Immunogen:Purified recombinant fragment of human PDK1 expressed in E. Coli. Formulation:Ascitic fluid containing 0.03% sodium azide. Application WB:1/500 - 1/2000 IHC:1/200 - 1/1000 ICC:1/200 - 1/1000 FCM:1/200 - 1/400 ELISA:1/10000