CDH17抗体;CDH17 Polyclonal Antib

Description This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine. Alternative splicing results in multiple transcript variants. References 1. Cancer Biol Ther. 2013 Mar;14(3):262-70.2. Mod Pathol. 2008 Nov;21(11):1379-86. Specification Aliases:HPT1; CDH16; HPT-1 Entrez GeneID:1015 Swissprot:Q12864 clone:7D10E1 WB Predicted band size:92.2kDa Host/Isotype:Mouse IgG1 Antibody Type:Primary antibody Storage:Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. Species Reactivity:Human Immunogen:Purified recombinant fragment of human CDH17 (AA: extra(600-707)) expressed in E. Coli. Formulation:Purified antibody in PBS with 0.05% sodium azide. Application IHC:1/200 - 1/1000 ELISA:1/10000