DAGLB抗体;DAGLB Polyclonal Antib

Description Members of the AB hydrolase superfamily have diverse catalytic functions and play a crucial role in the metabolism of lipids. DAGLβ (diacylglycerol lipase beta), also known as KCCR13L, is a 672 amino acid multi-pass membrane protein that belongs to the AB hydrolase superfamily. DAGLβ uses calcium as a cofactor to catalyze the hydrolysis of diacylglycerol (DAG) to 2-arachidonoyl-glycerol (2-AG), a reaction that is required for axonal growth and for retrograde synaptic signaling at mature synapses. DAGLβ functions at an optimal pH of 7 and its activity is inhibited by p-hydroxy-mercuri-benzoate and HgCl2, but not PMSF. There are three isoforms of DAGLβ that are produced as a result of alternative splicing events. Specification Aliases:KCCR13L; DAGLBETA Swissprot:Q8NCG7 Host/Isotype:Rabbit IgG Antibody Type:Primary antibody Storage:Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. Species Reactivity:Human Immunogen:Synthetic peptide of human DAGLB Formulation:pH7.4 PBS, 0.05% NaN3, 40% Glycerol Application IHC:1/20-1/100 ELISA:1/5000-1/10000