XRN1抗体;XRN1 Polyclonal Antibod

Description This gene encodes a member of the 5'-3' exonuclease family. The encoded protein may be involved in replication-dependent histone mRNA degradation, and interacts directly with the enhancer of mRNA-decapping protein 4. In addition to mRNA metabolism, a similar protein in yeast has been implicated in a variety of nuclear and cytoplasmic functions, including homologous recombination, meiosis, telomere maintenance, and microtubule assembly. Mutations in this gene are associated with osteosarcoma, suggesting that the encoded protein may also play a role in bone formation. Alternative splicing results in multiple transcript variants. Specification Aliases: SEP1 Swissprot:Q8IZH2 WB Predicted band size:194 kDa Host/Isotype:Rabbit IgG Antibody Type:Primary antibody Storage:Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. Species Reactivity:Human, Mouse Immunogen:Synthetic peptide of human XRN1 Formulation:pH7.4 PBS, 0.05% NaN3, 40% Glycerol Application WB:1/200-1/1000 ELISA:1/5000-1/10000