NOS1抗体;NOS1 Polyclonal Antibod

Description The protein encoded by this gene belongs to the family of nitric oxide synthases, which synthesize nitric oxide from L-arginine. Nitric oxide is a reactive free radical, which acts as a biologic mediator in several processes, including neurotransmission, and antimicrobial and antitumoral activities. In the brain and peripheral nervous system, nitric oxide displays many properties of a neurotransmitter, and has been implicated in neurotoxicity associated with stroke and neurodegenerative diseases, neural regulation of smooth muscle, including peristalsis, and penile erection. This protein is ubiquitously expressed, with high level of expression in skeletal muscle. Multiple transcript variants that differ in the 5' UTR have been described for this gene but the full-length nature of these transcripts is not known. Additionally, alternatively spliced transcript variants encoding different isoforms (some testis-specific) have been found for this gene. References 1.J Neurochem. 2013 Aug;126(3):318-30. 2.J Leukoc Biol. 2012 Jun;91(6):947-56. Specification Aliases:NOS; bNOS; nNOS; IHPS1; N-NOS; NC-NOS Entrez GeneID:4842 Swissprot:P29475 clone:2E11G6 WB Predicted band size:161kDa Host/Isotype:Mouse IgG1 Antibody Type:Primary antibody Storage:Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. Species Reactivity:Human Immunogen:Purified recombinant fragment of human NOS1 (AA: 17-153) expressed in E. Coli. Formulation:Purified antibody in PBS with 0.05% sodium azide Application ICC:1/200 - 1/1000 FCM:1/200 - 1/400 ELISA:1/10000