CHRNA6抗体;CHRNA6 Polyclonal Ant

Description This gene encodes an alpha subunit of neuronal nicotinic acetylcholine receptors. These receptors consist of five subunits and function as ion channels involved in neurotransmission. The encoded protein is a subunit of neuronal nicotinic acetylcholine receptors that mediate dopaminergic neurotransmission and are activated by acetylcholine and exogenous nicotine. Alternatively spliced transcript variants have been observed for this gene. Single nucleotide polymorphisms in this gene have been associated with both nicotine and alcohol dependence. References 1.Mol Brain. 2014 May 2;7:35. 2.Mol Psychiatry. 2010 Jan;15(1):6-8. Specification Aliases:CHNRA6 Entrez GeneID:8973 Swissprot:Q15825 clone:5B6G8 WB Predicted band size:57kDa Host/Isotype:Mouse IgG1 Antibody Type:Primary antibody Storage:Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. Species Reactivity:Human Immunogen:Purified recombinant fragment of human CHRNA6 (AA: 26-239) expressed in E. Coli. Formulation:Purified antibody in PBS with 0.05% sodium azide Application IHC:1/200 - 1/1000 ICC:1/100 - 1/500 FCM:1/200 - 1/400 ELISA:1/10000