GRM5抗体;GRM5 Polyclonal Antibod

Description This gene encodes a member of the G-protein coupled receptor 3 protein family. The encoded protein is a metabatropic glutamate receptor, whose signaling activates a phosphatidylinositol-calcium second messenger system. This protein may be involved in the regulation of neural network activity and synaptic plasticity. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. A pseudogene of this gene has been defined on chromosome 11. Alternative splicing results in multiple transcript variants. References 1.Curr Alzheimer Res. 2014;11(7):694-705. 2.Int J Neuropsychopharmacol. 2014 Dec;17(12):1915-22. Specification Aliases:mGlu5; GPRC1E; MGLUR5; PPP1R86 Entrez GeneID:2915 Swissprot:P41594 clone:1A11D10 WB Predicted band size:132.5kDa Host/Isotype:Mouse IgG1 Antibody Type:Primary antibody Storage:Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. Species Reactivity:Human Immunogen:Purified recombinant fragment of human GRM5 (AA: extra 458-580) expressed in E. Coli. Formulation:Purified antibody in PBS with 0.05% sodium azide Application IHC:1/200 - 1/1000 ICC:1/200 - 1/1000 ELISA:1/10000